Evidence map›Paper›PMID 40271204›Full record

ArticleInternet interventions2025

The promise and challenges of computer mouse trajectories in DMHIs - A feasibility study on pre-treatment dropout predictions.

Kirsten Zantvoort, Jennifer J Matthiesen, Pontus Bjurner, Marie Bendix, Ulf Brefeld, Burkhardt Funk, Viktor Kaldo

Abstract read
In one paragraph

Article in Internet interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kirsten ZantvoortInstitute of Information Systems, Leuphana University, Lüneburg, Germany.
Jennifer J MatthiesenInstitute of Information Systems, Leuphana University, Lüneburg, Germany.
Pontus BjurnerCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Sweden.
Marie BendixCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Sweden.
Ulf BrefeldInstitute of Information Systems, Leuphana University, Lüneburg, Germany.
Burkhardt FunkInstitute of Information Systems, Leuphana University, Lüneburg, Germany.
Viktor KaldoCentre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the impetus of Digital Mental Health Interventions (DMHIs), complex data can be leveraged to improve and personalize mental health care. However, most approaches rely on a very limited number of often costly features. Computer mouse trajectories can be unobtrusively and cost-efficiently gathered and seamlessly integrated into current baseline processes. Empirical evidence suggests that mouse movements hold information on user motivation and attention, both valuable aspects otherwise difficult to measure at scale. Further, mouse trajectories can already be collected on pre-treatment questionnaires, making them a promising candidate for early predictions informing treatment allocation. Therefore, this paper discusses how to collect and process mouse trajectory data on questionnaires in DMHIs. Covering different complexity levels, we combine hand-crafted features with non-sequential machine learning models, as well as spatiotemporal raw mouse data with state-of-the-art sequential neural networks. The data processing pipeline for the latter includes task-specific pre-processing to convert the variable length trajectories into a single prediction per user. As a feasibility study, we collected mouse trajectory data from 183 patients filling out a pre-intervention depression questionnaire. While the hand-crafted features slightly improve baseline predictions, the spatiotemporal models underperform. However, considering our small data set size, we propose more research to investigate the potential value of this novel and promising data type and provide the necessary steps and open-source code to do so.

Indexed as

DropoutE-mental healthICBTMachine learningPrediction

Identifiers

PMID40271204
PMCPMC12017972

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.