Evidence map›Paper›PMID 40270577›Full record

ArticleRegenerative biomaterials2025

Facile construction of manganese-based contrast agent with high

Chunwei Wu, Jie Zhong, Jianing Li, Yande Luo, Junyao Wang, Xiaodie Zeng, Jiaji Mao, Jianping Lu, Junyao Xu, Changqiang Wu and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chunwei WuSchool of Materials Science and Engineering, Center for Functional Biomaterials, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, P. R. China.
Jie ZhongMedical Imaging Key Laboratory of Sichuan Province and School of Medical Imaging, North Sichuan Medical College, Nanchong 637000, P. R. China.
Jianing LiDepartment of Radiology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, P. R. China.
Yande LuoSchool of Biomedical Engineering, Guangzhou Medical University, Guangzhou 511495, P. R. China.
Junyao WangSchool of Materials Science and Engineering, Center for Functional Biomaterials, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, P. R. China.
Xiaodie ZengSchool of Materials Science and Engineering, Center for Functional Biomaterials, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, P. R. China.
Jiaji MaoDepartment of Radiology, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, P. R. China.
Jianping LuSchool of Materials Science and Engineering, Center for Functional Biomaterials, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, P. R. China.
Junyao XuDepartment of Hepatobiliary Surgery, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou 510150, P. R. China.
Changqiang WuMedical Imaging Key Laboratory of Sichuan Province and School of Medical Imaging, North Sichuan Medical College, Nanchong 637000, P. R. China.ORCID https://orcid.org/0000-0002-6363-2721
Zhiyong WangSchool of Materials Science and Engineering, Center for Functional Biomaterials, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Sun Yat-sen University, Guangzhou 510275, P. R. China.ORCID https://orcid.org/0000-0002-0717-6549

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address the limitations of low relaxivity and physiological toxicity in commercial gadolinium-based contrast agents for magnetic resonance imaging (MRI), a novel manganese chelate macromolecular system was developed using a flash nanopreparation technique. Herein, the approach applying an instantaneous fluid device incorporated gallic acid, dopamine and Mn

Indexed as

contrast agentsflash nanopreparationmagnetic resonance imagingnanocompositepolyhenol

Identifiers

PMID40270577
PMCPMC12017619

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.