Evidence map›Paper›PMID 40270568›Full record

ArticleFrontiers in psychiatry2025

Acute myasthenia caused by lithium: a case report.

Jiashu Yao, Ruihuan Ye, Xihao Mao, Mingmin Jin, Rong Yan, Yuedi Shen, Ning Dai, Wei Chen

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiashu YaoDepartment of Psychiatry, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Ruihuan YeDepartment of Psychiatry, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Xihao MaoDepartment of Psychiatry, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Mingmin JinDepartment of Psychiatry, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Rong YanDepartment of Psychiatry, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Yuedi ShenThe Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Ning DaiDepartment of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Wei ChenDepartment of Psychiatry, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of an 18-year-old female patient with bipolar disorder who developed recurrent acute myasthenia after taking lithium. The myasthenia resolved upon discontinuation of lithium, and this occurred twice. The results of the cranial magnetic resonance imaging (MRI), multiple sleep latency test, polysomnography, ambulatory electroencephalogram (EEG), and other tests were all negative. In summary, the patient's acute myasthenia was attributed to lithium use. Unlike previously reported cases of lithium-induced chronic and mild myasthenia symptoms, this case involved acute and widespread myasthenia with falls as the primary manifestation. The mechanism may be related to the effect of lithium on acetylcholine receptor (AChR) metabolism, neurotransmitter release, and neuromuscular junction (NMJ) stability.

Indexed as

lithiummyasthenianeuromuscular junctionside effectsynaptic function

Identifiers

PMID40270568
PMCPMC12014660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.