Evidence map›Paper›PMID 40270437›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Metal-Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy.

Qilu Wu, Yuxiao Feng, Mathilde Lepoitevin, Meng Yu, Christian Serre, Jun Ge, Yuan Huang

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Metal-Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qilu WuKey Lab for Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing, 100084, P. R. China.
Yuxiao FengKey Lab for Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing, 100084, P. R. China.
Mathilde LepoitevinInstitut des Matériaux Poreux de Paris, ENS, ESPCI Paris, CNRS, PSL University, Paris, 75005, France.
Meng YuInstitut des Matériaux Poreux de Paris, ENS, ESPCI Paris, CNRS, PSL University, Paris, 75005, France.
Christian SerreInstitut des Matériaux Poreux de Paris, ENS, ESPCI Paris, CNRS, PSL University, Paris, 75005, France.
Jun GeKey Lab for Industrial Biocatalysis, Ministry of Education, Department of Chemical Engineering, Tsinghua University, Beijing, 100084, P. R. China.
Yuan HuangCardiac Surgery Centre, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, No.167 North Lishi Road, Xicheng District, Beijing, 100037, P. R. China.ORCID https://orcid.org/0000-0002-1420-8932

Funding

Beijing Natural Science Foundation Z240030National Key R&D Program of China 2023YFA0913600National Natural Science Foundation of China 22425803National Natural Science Foundation of China 82300345Shenzhen Science and Technology Program KCXFZ20240903093102004
6 · The paper itself

Abstract

Cardiovascular disease (CVD) is one of the most critical diseases which is the predominant cause of death in the world. Early screening and diagnosis of the disease and effective treatment after diagnosis play an important role in the patient's recovery. Metal-organic frameworks (MOFs), a kind of hybrid ordered micro or meso-porous materials, constructed by metal nodes or clusters with organic ligands, due to their special features like high porosity and specific surface area, open metal sites, or ligand tunability, are widely used in various areas including gas storage, catalysis, sensors, biomedicine. Recently, advances in MOFs are bringing new developments and opportunities for the healthcare industry including the theranostic of CVD. In this review, the applications of MOFs are illustrated in the diagnosis and therapy of CVD, including biomarker detection, imaging, drug delivery systems, therapeutic gas delivery platforms, and nanomedicine. Also, the toxicity and biocompatibility of MOFs are discussed. By providing a comprehensive summary of the role played by MOFs in the diagnosis and treatment of CVDs, it is hoped to promote the future applications of MOFs in disease theranostics, especially in CVDs.

Indexed as

Cardiovascular DiseasesMetal-Organic FrameworksAnimalsDrug Delivery SystemsHumansTheranostic NanomedicineMetal-Organic Frameworksbiocompatibilitycardiovascular diseasediagnosismetal–organic frameworkstherapy

Identifiers

PMID40270437
PMCPMC12165090

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.