Evidence map›Paper›PMID 40270264›Full record

ArticleCirculation research2025

Novel Humanized Aortic Valve Calcification Model.

Dunpeng Cai, Lindsey Saint, John Markley, Shi-You Chen

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dunpeng CaiDepartment of Surgery, University of Missouri School of Medicine, Columbia, MO (D.C., L.S., J.M., S.-Y.C.).
Lindsey SaintDepartment of Surgery, University of Missouri School of Medicine, Columbia, MO (D.C., L.S., J.M., S.-Y.C.).ORCID 0009-0008-0995-1319
John MarkleyDepartment of Surgery, University of Missouri School of Medicine, Columbia, MO (D.C., L.S., J.M., S.-Y.C.).ORCID 0009-0009-1119-0018
Shi-You ChenDepartment of Surgery, University of Missouri School of Medicine, Columbia, MO (D.C., L.S., J.M., S.-Y.C.).ORCID 0000-0002-0297-8649

Funding

Novel mechanism of smooth muscle phenotypic modulation and vascular remodelingR01HL119053 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI CHEN, SHIYOU · 2014 to 2023
$3.8M
Novel Mechanisms underlying abdominal aortic aneurysm progressionR01HL173025 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI Shiyou Chen · 2024 to 2026
$1.9M
Targeting response gene to complement 32 to alleviate vascular remodelingR01HL176673 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI Shiyou Chen · 2025 to 2026
$1.3M
RECK as a Therapeutic Target for AtherosclerosisR01HL170056 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI Chandrasekar Bysani, Shiyou Chen · 2025 to 2026
$1.3M
BLRD VA I01 BX006161NHLBI NIH HHS R01 HL119053NHLBI NIH HHS R01 HL170056NHLBI NIH HHS R01 HL173025NHLBI NIH HHS R01 HL176673
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

angioplastyimmunityinformed consentmodels, animalsutures

Identifiers

PMID40270264
PMCPMC12442895

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.