Evidence map›Paper›PMID 40270182›Full record

ArticleBiomacromolecules2025

Robust Photocleavable Linkers for DNA Synthesis: Enabling Visible Light-Triggered Antisense Oligonucleotide Release in 3D DNA Nanocages.

Hoi Man Leung, Hau Yi Chan, Maxime Klimezak, Ling Sum Liu, Pierre Karam, Alexandre Specht, Frédéric Bolze, Pik Kwan Lo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomacromolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hoi Man LeungDepartment of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Hong Kong, China.
Hau Yi ChanDepartment of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Hong Kong, China.
Maxime KlimezakLaboratoire de Chémo-Biologie Synthétique et Thérapeutique (CBST), Équipe Nanoparticules Intelligentes, CNRS, CBST UMR 7199, Université de Strasbourg, Illkirch, Cedex F-67401, France.
Ling Sum LiuDepartment of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Hong Kong, China.
Pierre KaramDepartment of Chemistry, American University of Beirut, Beirut 1107 2020, Lebanon.ORCID 0000-0003-4550-7641
Alexandre SpechtLaboratoire de Chémo-Biologie Synthétique et Thérapeutique (CBST), Équipe Nanoparticules Intelligentes, CNRS, CBST UMR 7199, Université de Strasbourg, Illkirch, Cedex F-67401, France.ORCID 0000-0001-5056-5278
Frédéric BolzeLaboratoire de Chémo-Biologie Synthétique et Thérapeutique (CBST), Équipe Nanoparticules Intelligentes, CNRS, CBST UMR 7199, Université de Strasbourg, Illkirch, Cedex F-67401, France.ORCID 0000-0002-7955-4668
Pik Kwan LoDepartment of Chemistry and State Key Laboratory of Marine Pollution, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong, Hong Kong, China.ORCID 0000-0001-5255-1718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We synthesized new

Indexed as

DNANanostructuresOligonucleotides, AntisenseLightPhotolysisDNAOligonucleotides, Antisense

Identifiers

PMID40270182
PMCPMC12076501

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.