Evidence map›Paper›PMID 40270003›Full record

ArticleJournal of veterinary internal medicine

Clinical Signs, Advanced Diagnostic Imaging Findings, Treatment, and Outcome of Mycotic Discospondylitis in 11 Dogs.

Samuel Okonji, Andrea Di Paola, Silvia Benini, Antonella Gallucci, Alberto Cauduro, Cristian Falzone, Teresa Gagliardo, Gualtiero Gandini

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samuel OkonjiDipartimento di Scienze Mediche Veterinarie, Department of Veterinary Medical Sciences, Università degli Studi di Bologna, Ozzano dell'Emilia, Italy.ORCID https://orcid.org/0009-0004-0308-9298
Andrea Di PaolaNeurovet, Milano, Italy.
Silvia BeniniDipartimento di Scienze Mediche Veterinarie, Department of Veterinary Medical Sciences, Università degli Studi di Bologna, Ozzano dell'Emilia, Italy.
Antonella GallucciCentro Veterinario Professionale La Fenice, Assemini, Italy.
Alberto CauduroNeurovet, Milano, Italy.
Cristian FalzoneClinica Veterinaria Pedrani Diagnostica Piccoli Animali Srl, Thiene, Italy.
Teresa GagliardoDiagnostic Center Palermovet, Palermo, Italy.
Gualtiero GandiniDipartimento di Scienze Mediche Veterinarie, Department of Veterinary Medical Sciences, Università degli Studi di Bologna, Ozzano dell'Emilia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiscospondylitis refers to inflammation of the intervertebral disc and adjacent vertebral endplates. The literature on mycotic discospondylitis (MD) in dogs is limited.

objectiveTo describe clinical and advanced diagnostic imaging findings, therapeutic strategies, and outcomes in dogs with a confirmed diagnosis of MD. ANIMALS: Eleven client-owned dogs with a diagnosis of MD. MATERIALS AND

methodsMedical records from five veterinary neurological referral centers were retrospectively reviewed between 2017 and 2024. The confirmed diagnosis of MD was based on clinical and magnetic resonance imaging (MRI) findings and the detection of fungal hyphae in urine, intervertebral disc, or cerebrospinal fluid (CSF).

resultsGerman shepherd (GS) were the most prevalent breed (7/11). Pain was the main clinical sign reported in all dogs, associated with gait abnormalities in 9 dogs. T3-L3 neuroanatomical localization was described in 10 dogs. MRI showed multiple intervertebral disc involvement in 7 dogs. Fungal hyphae were identified in urine sediment in 5 dogs and by CT-guided needle aspiration of the affected disc in 2 dogs. Aspergillus spp. was the most common etiological agent being reported in 7 dogs. Ten dogs were dead at the end of data analysis, with a median survival time of 30 days. CONCLUSION AND CLINICAL IMPORTANCE: This case series demonstrates the necessity of accurate diagnosis to set an appropriate treatment, despite the poor prognosis after antifungal therapy.

Indexed as

Dog DiseasesSpondylitisAnimalsAntifungal AgentsAspergillosisDogsFemaleMagnetic Resonance ImagingMaleRetrospective StudiesAntifungal Agentsantimycotic treatmentaspergillosisdiskospondylitisfungalmicrobiologysystemic mycosis

Identifiers

PMID40270003
PMCPMC12018769

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.