Evidence map›Paper›PMID 40269992›Full record

SynthesisEuropean journal of medical research2025

CT-derived adipose tissue characteristics and TAVI all-cause mortality and complications: a systematic review.

Matej Pekar, Piotr Branny, Otakar Jiravsky, Radim Spacek, Jan Alexander Mohr, Ivan Ranic, Bogna Jiravska Godula, Alica Cesnakova Konecna, Marek Kantor, Jan Hecko and 3 more

Abstract readSystematic Review
In one paragraph

Synthesis in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Your CT scans are hiding crucial TAVI survival data: Are you looking?American heart journal plus : cardiology research and practice · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Matej Pekar *Hospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Piotr Branny *Hospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Otakar JiravskyHospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic. otakar.jiravsky@npo.agel.cz.
Radim SpacekHospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Jan Alexander MohrHospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Ivan RanicHospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Bogna Jiravska GodulaHospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Alica Cesnakova KonecnaHospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Marek KantorHospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Jan HeckoHospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Radek NeuwirthHospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Libor SknourilHospital AGEL Třinec-Podlesí, Konská 453, 739 61, Třinec, Czech Republic.
Jan NovakDepartment of Physiology Faculty of Medicine Masaryk University Kamenice, 5 625 00, Brno, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcatheter Aortic Valve Implantation (TAVI) has revolutionized severe aortic stenosis treatment, but risk stratification remains challenging. This systematic review examined the association between computed tomography (CT)-derived adipose tissue parameters and TAVI outcomes. We searched major databases for studies on visceral (VAT), subcutaneous (SAT), and intramuscular (IMAT) adipose tissue parameters and post-TAVI outcomes. Fourteen studies (9692 patients) were included. Higher SAT area/volume was consistently associated with better survival (5 studies, HR range: 0.83-2.77, p < 0.05). Lower SAT and VAT density also correlated with better survival (5 and 4 studies, respectively, HR range: 1.31-1.46, p < 0.05). VAT area showed mixed results. A VAT:SAT ratio < 1 was associated with better cardiovascular outcomes in one study. Lower IMAT index correlated with shorter hospital stays in a single study. This review reveals complex relationships between adipose tissue parameters and TAVI outcomes. Lower adipose tissue density and higher subcutaneous adiposity were most consistently associated with better outcomes. These findings suggest that detailed analysis of adipose tissue characteristics may enhance risk stratification in TAVI candidates.

Indexed as

Adipose TissueAortic Valve StenosisPostoperative ComplicationsTomography, X-Ray ComputedTranscatheter Aortic Valve ReplacementHumansAdipose tissue parametersCT-derived body compositionRisk stratificationSubcutaneous fatTAVI outcomesVisceral fat

Identifiers

PMID40269992
PMCPMC12020199

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.