SynthesisCritical care (London, England)2025
Prevalence and incidence of cognitive impairment following acute respiratory distress syndrome of any cause: a systematic review and meta-analysis.
Synthesis in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed.
- Impact of ultra-low tidal volume ventilation on 1-year functional outcome in COVID-19 ARDS patients. A long-term follow-up analysis of a randomized controlled trial.Critical care (London, England) · 2026Trial
- Experimental model of ventilator-induced lung injury induces proteomic signatures of neurodegeneration in the hippocampus.Intensive care medicine experimental · 2026Article
- Burden of and risk factors for neurological complications in critical illness.Intensive care medicine · 2026Review
- A cross-sectional analysis of multidimensional clinical profiles of older adults engaged in structured post-ICU follow-up: age is not the whole story.European geriatric medicine · 2026Article
- Creation of a dedicated post-intensive care geriatric unit (PIGU), proof of concept and preliminary results.European geriatric medicine · 2026Article
- Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents.Brain and behavior · 2026Review
- Rethinking Mechanical Ventilation: Can Ventilation Mode Influence Long-Term Cognitive Outcomes in ICU Patients with COVID-19?Journal of clinical medicine · 2026Article
- An augmented rehabilitation package incorporating immersive virtual reality during early recovery after ARDS: A randomized controlled trial.Annals of intensive care · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this systematic review and meta-analysis is to synthesize and appraise the evidence on prevalence of cognitive impairment following acute respiratory distress syndrome (ARDS) of any cause.
methodsWe systematically searched PubMed, Scopus, and Web of Science for observational studies focused on cognitive impairment in adult survivors of ARDS. Risk of bias and certainty of evidence (GRADE) were assessed. A meta-analysis using a random effects model was performed to estimate the overall prevalence of cognitive impairment after ARDS, with subgroup analyses for COVID-19-related ARDS (C-ARDS). Additionally, a meta-regression was conducted to assess the influence of demographic and clinical predictors on cognitive outcomes. Heterogeneity was assessed using τ
resultsWe identified 14 studies with 1451 participants, with 650 participants (range: 13-98) included in the analyses. In the subgroup of C-ARDS, 12 studies with 563 participants (range: 13-98) were considered. The pooled prevalence of cognitive impairment following ARDS was 36% (95% CI 26-46%), with high heterogeneity between studies (I
conclusionsThis meta-analysis corroborates previous findings that cognitive impairment remains a persistent issue for ARDS survivors. The prevalence of cognitive impairments following ARDS highlights the importance of future research to unravel the complex underlying mechanisms contributing to these deficits and to develop targeted strategies for prevention and rehabilitation in survivors.
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