Evidence map›Paper›PMID 40269963›Full record

ArticleChild and adolescent psychiatry and mental health2025

Understanding the impact of COVID-19 on comorbid depression, anxiety and eating disorders in adolescent psychiatric inpatients: a network analysis.

Charlotte M K Milewczyk, Martin Holtmann, Tanja Legenbauer, Laura M Derks

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Article in Child and adolescent psychiatry and mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Charlotte M K MilewczykDepartment for Child and Adolescent Psychiatry, Psychosomatic and Psychotherapy, LWL University Hospital of the Ruhr University Bochum, Heithofer Allee 64, 59071, Hamm, Germany. charlotte.milewczyk@ruhr-uni-bochum.de.
Martin HoltmannDepartment for Child and Adolescent Psychiatry, Psychosomatic and Psychotherapy, LWL University Hospital of the Ruhr University Bochum, Heithofer Allee 64, 59071, Hamm, Germany.
Tanja Legenbauer *Department for Child and Adolescent Psychiatry, Psychosomatic and Psychotherapy, LWL University Hospital of the Ruhr University Bochum, Heithofer Allee 64, 59071, Hamm, Germany.
Laura M Derks *Department for Child and Adolescent Psychiatry, Psychosomatic and Psychotherapy, LWL University Hospital of the Ruhr University Bochum, Heithofer Allee 64, 59071, Hamm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany studies have aimed to understand the impact of the COVID-19 pandemic on mental health. However, less research has focused on the changes in symptom clusters of comorbid disorders. To understand the impact of the COVID-19 pandemic it is necessary to evaluate the relationships between symptoms of comorbid disorders. This was the first study to compare comorbidity networks of depression, anxiety and eating disorder (ED) symptoms to investigate the overall connectivity of symptoms before and during the onset of the pandemic.

methodsSelf-report questionnaire data from 1361 adolescent psychiatric inpatients (M

resultsA significantly higher network density and overall connectivity were found in the peri pandemic sample. Links between feelings of failure in the depression cluster and worry what other people think in the anxiety cluster as well as between difficulties getting rid of bad/ silly thoughts in the anxiety cluster and suicidal thoughts in the depression cluster emerged as the strongest pathways in both networks. Body image disturbance emerged as the strongest bridge symptom for eating disorders in both networks. There were no significant differences in the most prominent core and bridge symptoms between the networks, indicating a high stability of core symptoms and pathways across circumstances.

conclusionsOur findings suggest a multidimensional relationship between symptoms of depression, anxiety, and eating disorders. The persistence of symptom pathways after the onset of the pandemic implies that these pathways may be responsible for the occurrence of comorbidity and should be primary targets of psychotherapy for affected patients. Addressing core and bridge symptoms in the therapy of comorbid disorders should be a priority and may be more effective than conventional treatment strategies.

Indexed as

AdolescenceAnxietyComorbidityCOVID-19DepressionEating disorderNetwork analysis

Identifiers

PMID40269963
PMCPMC12020227

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.