ArticleJournal of orthopaedic surgery and research2025
First metacarpal extension-abduction osteotomy effect on joint remodeling and articular cartilage repair in thumb carpometacarpal osteoarthritis.
Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Pre- and postoperative 4D CT analysis of thumb CMC joint kinematics after first metacarpal extension osteotomy.Archives of orthopaedic and trauma surgery · 2026Observational
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe first metacarpal osteotomy is a joint-preserving surgery for thumb carpometacarpal (CMC) osteoarthritis that improves pain and function. However, its effects on joint remodeling and articular cartilage repair under physiological conditions remain unclear. This study aimed to clarify these aspects using computed tomography (CT)-based subchondral bone density analysis and arthroscopic evaluation.
methodsFifteen hands of 14 patients who underwent a first metacarpal extension-abduction osteotomy for thumb CMC osteoarthritis were included. CT scans were performed preoperatively and one year postoperatively to assess changes in subchondral bone density (measured in Hounsfield units [HU]) across nine regions of the first metacarpal and trapezium articular surfaces. Arthroscopic evaluation of the articular cartilage was performed at the time of osteotomy and at implant removal one year postoperatively using the International Cartilage Repair Society (ICRS) grading scale.
resultsPreoperatively, higher HU values (median [interquartile range]) were observed in the palmar regions of the first metacarpal (758 [643-803] HU) and the central regions of the trapezium (898 [867-960] HU). One year after osteotomy, these values decreased significantly in these initially high-stress regions (first metacarpal palmar regions: 433 [307-475] HU, p <.001; trapezium central regions: 571 [508-649] HU, p <.001; Wilcoxon matched-pairs signed rank test), indicating a more uniform stress distribution. Arthroscopic evaluation revealed improvements in ICRS grade in five out of nine cases on the metacarpal side and four out of nine cases on the trapezium side.
conclusionsThe first metacarpal extension-abduction osteotomy alters the abnormal stress distribution patterns in thumb CMC osteoarthritis, leading to a more uniform stress distribution across the joint. Arthroscopic findings suggest that articular cartilage repair may occur following osteotomy. These results provide new insights into the mechanisms underlying the clinical benefits of this procedure and support its use as a joint-preserving surgery for thumb CMC osteoarthritis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.