ArticleBMC pregnancy and childbirth2025
Elective cesarean section and bottle-feeding do not reduce infection of hepatitis B in infants of high viremic mothers: a retrospective study.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundStudies on the issue of whether elective cesarean section (ECS) may reduce mother-to-child transmission (MTCT) of HBV in infants of carrier mothers with high viremia (HBV DNA > 2 × 10
methodsIn total, 460 mothers with HBV DNA > 2 × 10
resultsOf the 462 infants, 214 (46.3%) were delivered by ECS and 178 (38.5%) were exclusively bottle-fed. Overall, 11 (2.4%) of 462 infants were HBsAg positive at 9.9 ± 2.4 month age. The MTCT rate (2.0%, 5/248) in vaginally delivered infants was similar to that (2.8%, 6/214) in infants delivered with ECS (χ
conclusionsWith timely immunoprophylaxis, ECS and bottle-feeding cannot reduce MTCT of HBV in infants born to high viremic mothers without antiviral therapy. ECS or bottle-feeding should not be recommended for the prevention of perinatal HBV infection.
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