Evidence map›Paper›PMID 40269785›Full record

ArticleBMC complementary medicine and therapies2025

The potential of blackcurrant, fig, and grape leaf extracts in the development of new preparations for overcoming antibiotic resistance and enhancing the efficacy of chemotherapeutic agents.

Mikayel Ginovyan, Silvard Tadevosyan, Anahit Shirvanyan, Anush Babayan, Barbara Kusznierewicz, Izabela Koss-Mikołajczyk, Marika Mróz, Agnieszka Bartoszek, Naira Sahakyan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mikayel GinovyanDepartment of Biochemistry, Microbiology and Biotechnology, Biology Faculty, Yerevan State University, 1 Alex Manoogian St, Yerevan, 0025, Armenia.
Silvard TadevosyanDepartment of Biochemistry, Microbiology and Biotechnology, Biology Faculty, Yerevan State University, 1 Alex Manoogian St, Yerevan, 0025, Armenia.
Anahit ShirvanyanDepartment of Biochemistry, Microbiology and Biotechnology, Biology Faculty, Yerevan State University, 1 Alex Manoogian St, Yerevan, 0025, Armenia.
Anush BabayanDepartment of Biochemistry, Microbiology and Biotechnology, Biology Faculty, Yerevan State University, 1 Alex Manoogian St, Yerevan, 0025, Armenia.
Barbara KusznierewiczDepartment of Food Chemistry, Technology and Biotechnology, Faculty of Chemistry, GdańSk University of Technology, Narutowicza 11/12, Gdańsk, 80-233, Poland.
Izabela Koss-MikołajczykDepartment of Food Chemistry, Technology and Biotechnology, Faculty of Chemistry, GdańSk University of Technology, Narutowicza 11/12, Gdańsk, 80-233, Poland.
Marika MrózDepartment of Food Chemistry, Technology and Biotechnology, Faculty of Chemistry, GdańSk University of Technology, Narutowicza 11/12, Gdańsk, 80-233, Poland.
Agnieszka BartoszekDepartment of Food Chemistry, Technology and Biotechnology, Faculty of Chemistry, GdańSk University of Technology, Narutowicza 11/12, Gdańsk, 80-233, Poland.
Naira SahakyanDepartment of Biochemistry, Microbiology and Biotechnology, Biology Faculty, Yerevan State University, 1 Alex Manoogian St, Yerevan, 0025, Armenia. sahakyannaira@ysu.am.

Funding

Science Committee of MESCS RA 21AG-4D027Science Committee of MESCS RA Basic support to Research Institute of Biology of the Yerevan State University
6 · The paper itself

Abstract

The presented study aimed to assess the efficacy of crude leaf hydroethanolic extracts from blackcurrant, fig, and grape leaves in reversing antibiotic resistance and enhancing chemotherapeutic efficacy. The viability tests were employed to assess the resistance-modifying properties of the extracts both in antibiotic-resistant bacterial cells and cancer cell-lines. To elucidate the potential mechanisms of the antibiotic modulatory activity of test extracts, the changes in H

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialFicusPlant ExtractsRibesVitisEscherichia coliHT29 CellsHumansMicrobial Sensitivity TestsPlant LeavesAnti-Bacterial AgentsPlant ExtractsAntibiotic-modulating activityCancer cell linesEscherichia coliFicus caricaResistance modifying propertyRibes nigrumVitis vinifera

Identifiers

PMID40269785
PMCPMC12016395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.