Evidence map›Paper›PMID 40269749›Full record

ArticleBMC primary care2025

Costs of the HEARTS hypertension program in primary care in Lampang province, Thailand.

Piyachon Aramrat, Chanchanok Aramrat, Thomas Taeksung Kim, Muhammad Jami Husain, Soumava Basu, Saudamini Dabak, Wanrudee Isaranuwatchai, Nutchar Wiwatkunupakarn, Apichard Sukonthasarn, Chaisiri Angkurawaranon and 2 more

Abstract read
In one paragraph

Article in BMC primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Piyachon AramratDepartment of Family Medicine, Faculty of Medicine, Chiang Mai University, 110 Intawaroros Road, Si Phum, Muang , 50200, Chiang Mai, Thailand.
Chanchanok AramratDepartment of Family Medicine, Faculty of Medicine, Chiang Mai University, 110 Intawaroros Road, Si Phum, Muang , 50200, Chiang Mai, Thailand.
Thomas Taeksung KimGlobal Health Center, Centers for Diseases Control and Prevention, Atlanta, United States of America.
Muhammad Jami HusainGlobal Health Center, Centers for Diseases Control and Prevention, Atlanta, United States of America.
Soumava BasuGlobal Health Center, Centers for Diseases Control and Prevention, Atlanta, United States of America.
Saudamini DabakHealth Intervention and Technology Assessment Program, Ministry of Public Health of Thailand, Bangkok, Thailand.
Wanrudee IsaranuwatchaiHealth Intervention and Technology Assessment Program, Ministry of Public Health of Thailand, Bangkok, Thailand.
Nutchar WiwatkunupakarnDepartment of Family Medicine, Faculty of Medicine, Chiang Mai University, 110 Intawaroros Road, Si Phum, Muang , 50200, Chiang Mai, Thailand.
Apichard SukonthasarnThai Hypertension Society, Bangkok, Thailand.
Chaisiri AngkurawaranonDepartment of Family Medicine, Faculty of Medicine, Chiang Mai University, 110 Intawaroros Road, Si Phum, Muang , 50200, Chiang Mai, Thailand. chaisiri.a@cmu.ac.th.
Deliana KostovaGlobal Health Center, Centers for Diseases Control and Prevention, Atlanta, United States of America.
Andrew E MoranResolve to Save Lives, New York, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2020, a pilot program for hypertension control was initiated in primary care facilities in Lampang Province, Thailand. The program followed the framework of the HEARTS program for standardized hypertension treatment, but the financial costs of the program are not well understood. This study evaluates the costs of the HEARTS approach compared to usual care to inform future scale-up efforts of the program.

methodsCost data were collected and analyzed using the HEARTS costing tool, a Microsoft Excel-based tool that supports activity-based costing of the HEARTS program from the health system perspective. Three scenarios were considered: usual care, the HEARTS regimen using standardized hypertension treatment with single-agent pills, and a sub-scenario of the HEARTS regimen using single-pill dual-drug combination pills. Costs are estimated as annual costs from the health system perspective in all Lampang primary care facilities.

resultsFor the usual care scenario, the HEARTS single-pill scenario, and the HEARTS combination-pill sub-scenario, the average annual medication cost per treated patient was USD 14.0 (THB 485), USD 13.8 (THB 479), and USD 14.3 (THB 497), respectively. Total program cost per primary care user was USD 13.6 (THB 472.7), THB USD 14.3 (494.5), and USD 14.4 (THB 499.9) across the three scenarios, respectively. The largest program cost driver (45-47% across the examined scenarios) was attributed to a comprehensive package of laboratory tests applied to all hypertension patients. Hypothetically, reducing test coverage from all hypertension patients (27% of primary care users) to 15% of primary care users (corresponding to the proportion of patients aged 65+) would reduce program cost per user from USD 14.3 to USD 12.0 in the HEARTS combination-pill scenario.

conclusionsCompared to usual care, HEARTS implementation costs include additional costs for staff training, which are balanced by lower medication expenditures using the HEARTS standardized regimen with single-agent pills. The HEARTS regimen using dual-drug combination pills was estimated to be slightly more costly due to the higher price of combination pills. Optimizing coverage of diagnostic tests and lowering the purchasing prices of combination-pill medicines are key areas for cost reduction in future scale-up efforts.

Indexed as

Antihypertensive AgentsHealth Care CostsHypertensionPrimary Health CareFemaleHumansMaleMiddle AgedPilot ProjectsThailandAntihypertensive AgentsCombination medicineCosting toolHEARTSHypertensionPrimary care

Identifiers

PMID40269749
PMCPMC12016098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.