Evidence map›Paper›PMID 40269715›Full record

ArticleBMC microbiology2025

Antibiotic resistance profiles and mutations that might affect drug susceptibility in metagenome-assembled genomes of Legionella pneumophila and Aeromonas species from municipal wastewater.

Evida Poopedi, Rian Pierneef, Tanusha Singh, Annancietar Gomba

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Evida PoopediDepartment of Oral and Maxillofacial Pathology, Oral Microbiology and Oral Biology, Sefako Makgatho Health Sciences University, Ga-Rankuwa, South Africa. evida.poopedi@smu.ac.za.
Rian PierneefDepartment of Biochemistry, Genetics and Microbiology, University of Pretoria, Pretoria, South Africa.
Tanusha SinghNational Institute for Occupational Health, National Health Laboratory Service, Johannesburg, South Africa.
Annancietar GombaNational Institute for Occupational Health, National Health Laboratory Service, Johannesburg, South Africa.

Funding

National Research Foundation 121333Water Research Commission K5/2885//3
6 · The paper itself

Abstract

Antibiotic resistance (AR) has emerged as a significant global health issue. Wastewater treatment plants (WWTPs) contain diverse bacterial communities, including pathogens, and have been identified as crucial reservoirs for the emergence and dissemination of AR. The present study aimed to identify antibiotic resistance genes (ARGs) and screen for the presence of mutations associated with AR in Legionella pneumophila and Aeromonas spp. from municipal wastewater. Metagenome-assembled genomes (MAGs) of L. pneumophila and Aeromonas spp. were reconstructed to investigate the molecular mechanisms of AR in these organisms. A total of 138 nonsynonymous single nucleotide variants (SNVs) in seven genes associated with AR and one deletion mutation in the lpeB gene were identified in L. pneumophila. In Aeromonas spp., two (aph(6)-Id and aph(3'')-Ib) and five (bla

Indexed as

AeromonasAnti-Bacterial AgentsDrug Resistance, BacterialLegionella pneumophilaMetagenomeWastewaterGenome, BacterialMicrobial Sensitivity TestsMutationAnti-Bacterial AgentsWastewaterAntibiotic resistanceMetagenome-assembled genomeMolecular mechanismsMunicipal wastewaterMutations

Identifiers

PMID40269715
PMCPMC12016116

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.