Evidence map›Paper›PMID 40269703›Full record

ArticleBMC geriatrics2025

Relationships of social isolation and loneliness with healthy aging among older adults.

Meng-Yuan Miao, Fei Fang, Jie-Qiong Lyu, Zhong-Yue Liu, Zhong-Xiao Wan, Li-Qiang Qin, Guo-Chong Chen, Hai-Peng Wang

Abstract read
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Meng-Yuan MiaoDepartment of Nutrition and Food Hygiene, School of Public Health, The First Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, 199 Ren'ai Road, Suzhou, 215123, China.
Fei FangDepartment of Nutrition and Food Hygiene, School of Public Health, The First Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, 199 Ren'ai Road, Suzhou, 215123, China.
Jie-Qiong LyuDepartment of Nutrition and Food Hygiene, School of Public Health, The First Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, 199 Ren'ai Road, Suzhou, 215123, China.
Zhong-Yue LiuDepartment of Nutrition and Food Hygiene, School of Public Health, The First Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, 199 Ren'ai Road, Suzhou, 215123, China.
Zhong-Xiao WanDepartment of Nutrition and Food Hygiene, School of Public Health, The First Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, 199 Ren'ai Road, Suzhou, 215123, China.
Li-Qiang QinDepartment of Nutrition and Food Hygiene, School of Public Health, The First Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, 199 Ren'ai Road, Suzhou, 215123, China.
Guo-Chong ChenDepartment of Nutrition and Food Hygiene, School of Public Health, The First Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, 199 Ren'ai Road, Suzhou, 215123, China. gcchen@suda.edu.cn.
Hai-Peng WangDepartment of Nutrition and Food Hygiene, School of Public Health, The First Affiliated Hospital of Soochow University, Suzhou Medical College of Soochow University, 199 Ren'ai Road, Suzhou, 215123, China. sonnywang83@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSocial isolation and loneliness have been recognized as important psychosocial factors affecting human health. We aimed to examine the relationships of social isolation and loneliness with the likelihood of healthy aging among older women and men.

methodsThe prospective study included 13,782 female and 11,838 male participants who were aged 64 years or older and had no major chronic diseases during recruitment of the UK Biobank (2006-2010). All participants were eligible to survive to age 80 before the latest follow-up (December 2021). Healthy aging was defined as survival to age 80 without major chronic diseases. Multivariable logistic regression models were used to evaluate the associations of social isolation, loneliness and their combination with the likelihood of healthy aging.

resultsA total of 9130 women (58.77%) and 6406 men (41.23%) achieved healthy aging. After adjusting for age and race/ethnicity, social isolation was associated with a significantly 20% and 14% lower likelihood of healthy aging among women and men, respectively, whereas among both sexes the associations for loneliness were similar but statistically non-significant. Among women, the association between loneliness and healthy aging varied by social isolation status (P

conclusionsA coexistence of social isolation and loneliness was associated with a substantially lower likelihood of healthy aging among women. Our findings highlight the importance of social support in extending women's healthspan beyond the management of traditional risk factors.

Indexed as

Healthy AgingLonelinessSocial IsolationAgedAged, 80 and overFemaleHumansMaleMiddle AgedProspective StudiesUnited KingdomHealthy agingInteractionLonelinessProspective cohort studySocial isolation

Identifiers

PMID40269703
PMCPMC12016190

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.