Evidence map›Paper›PMID 40269692›Full record

Observational studyBMC anesthesiology2025

Airway management in patients with surgical treatment of oral cavity carcinoma.

Patrick Sturm, Holger Gaessler, Christel Weiß, Alexander Schramm, Frank Wilde, Marcel Ebeling, Andreas Sakkas

Abstract readObservational Study
In one paragraph

Observational study in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Patrick SturmDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Ulm, Germany.
Holger GaesslerDepartment of Anaesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Therapy, Federal Armed Forces Hospital Ulm, Ulm, Germany.
Christel WeißMedical Statistics and Biomathematics, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany.
Alexander SchrammDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Ulm, Germany.
Frank WildeDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Ulm, Germany.
Marcel EbelingDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Ulm, Germany.
Andreas SakkasDepartment of Oral and Maxillofacial Surgery, University Hospital Ulm, Ulm, Germany. andreas.sakkas@uni-ulm.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLocal tumor-related anatomical changes can complicate the anesthetic airway management of patients with carcinoma of the oral cavity. The aim of this study was to investigate whether there are predictive factors for the occurrence of a difficult airway in this patient cohort and whether a difficult airway influences postoperative outcome. In addition, the influence of an intraoperative tracheostomy on postoperative outcome was to be analyzed.

methodsThe treatment records of 201 patients with oral cavity carcinoma who underwent surgery between 2012 and 2023 in a single center were retrospectively analyzed. The definition of difficult airway corresponded to the current S1 guideline of the German Society of Anesthesiology and Intensive Care Medicine from 2015. An association between possible predictive factors and a difficult airway was investigated. The influence of BMI, Mallampati score and Cormack/Lehane score on the number of intubation attempts was analyzed separately. Furthermore, the influence of a difficult airway on the duration of intubation and the duration of the postoperative inpatient stay as well as the postoperative ICU stay was investigated. In addition, the association between an intraoperative tracheostomy and the duration of intubation as well as the duration of the postoperative inpatient stay was analyzed.

resultsDifficult airway occurred in 15 patients (7,5%) and 136 (68%) underwent intraoperative tracheostomy. An indirect laryngoscopy was used in advance in 32,8% of the total patients and 45,4% of the patients undergoing revision surgery. Among the investigated variables, no predictive factors for a difficult airway could be identified. Regarding the number of intubation attempts required, a higher BMI and Mallampati score did not lead to increased number of intubation attempts; however, patients with a Cormack/Lehane score of 3 were significantly more likely to require 2 attempts than patients with a score of 1 or 2 (p = 0.0225). The success rate of first intubation attempt was 78% with videolaryngoscopy, compared to 95,5% when direct laryngoscopy was used (p = 0,0008). A difficult airway did not lead to prolonged postoperative ICU stay and total hospitalisation length. Patients with an intraoperative tracheostomy had a significantly longer mechanical ventilation and total hospitalisation length than patients without (p < 0.0001).

conclusionWithin the limitations of this study, no patient-specific predictors for a difficult airway were identified in patients with oral cavity carcinoma. Videolaryngoscopy in advance did not increase the success rate of the first intubation attempt compared to direct laryngoscopy. Despite this, videolaryngoscopy may be a preferable approach in this population, especially in patients undergoing revision surgeries. The results highlight the importance of a careful preoperative assessment with clearly defined criteria for a difficult airway and appropriate anaesthesiological preparation to avoid complications during intubation.

trial registrationEthics committee of the University of Ulm, approval reference: 115/23, approval date: 08.05.2023.

Indexed as

Airway ManagementMouth NeoplasmsAdultAgedFemaleHumansIntubation, IntratrachealLaryngoscopyLength of StayMaleMiddle AgedRetrospective StudiesTracheostomyAirway managementDifficult airwayOral cavity carcinomaTracheostomyVideolaryngoscopy

Identifiers

PMID40269692
PMCPMC12016132

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.