Observational studyBMC anesthesiology2025
Role of immature granulocytes in monitoring sepsis treatment.
Observational study in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Article
- Immature Granulocyte Trajectories Following Hemadsorption as Indicators of Immune Dysregulation and Mortality.Journal of clinical medicine · 2026Article
- The Role of Immature Granulocytes in Fibromyalgia: An Indicator of Subclinical Inflammation?Biomedicines · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSepsis is an organ dysfunction that impairs response to infection. Inflammatory biomarkers have been used to diagnose and monitor sepsis. The aim of the present study was to determine the role of immature granulocytes (IGs) in monitoring sepsis treatment.
methodsThis two-center, prospective, observational study included patients diagnosed with sepsis according to the Sepsis-3 criteria, who were followed-up in the adult intensive care units of the Bolu Izzet Baysal State Hospital and Bolu Izzet Baysal Training and Research Hospital (Bolu Merkez/Bolu, Türkiye). Laboratory investigation results, demographic information, treatment responses, and mortality were recorded. Patients were divided into 2 groups according to treatment: appropriate (group 1); and inappropriate (group 2). Differences in the number of IGs and IG% were compared. Differences with P < 0.05 were considered to be statistically significant for all analyses.
resultsThe study included 87 patients from 2 centers. The most common comorbidities were hypertension (54%) and 28-day mortality (37.9%). Empirical antibiotic therapy (43.7%) was appropriate for 38 patients (group 1) and 49 patients when the treatment was incorrect or inadequate (group 2). There were no significant differences between the groups in terms of laboratory investigation results on the day of treatment initiation. IG count and IG% on day 3 of treatment were significantly higher in group 2. Mortality was higher in patients with a high IG count (IG %) and in group 2.
conclusionIG% was a simple, inexpensive, and useful test for monitoring sepsis treatment and, in addition, IG count was also effective in predicting mortality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.