ArticleACS applied bio materials2025
Enzymatic Polymer Brush Interfaces for Electrochemical Sensing in Biofluids.
Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- XPS analysis of polymer brush coatings.Polymer chemistry · 2026Review
- Electrochemical Biosensor Based on Hairy Core-Shell Particles: Effect of Core Conductivity.Small science · 2026Article
- Responsive Polyelectrolyte Brushes in Applications: Functions, Stimuli, and Design Considerations.Advanced materials (Deerfield Beach, Fla.) · 2025Review
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Electrochemical sensors enable specific and sensitive detection of biological markers. However, most small molecule analytes are not electroactive. Therefore, enzymes are widely used for selective breakdown of the markers into electro-active species. However, it has proven difficult to design a sensor interface where any enzyme can be controllably immobilized in high amounts with preserved activity. In addition, most interfaces cease to function in biofluids due to "fouling" of the sensor surface. Here we present a generic strategy employting polymer brushes for enzymatic electrochemical sensing which resolves these issues. Generic conjugation chemistry is used to covalently bind large amounts of enzymes (>1 μg/cm
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Registered trials
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