ArticleNature2025
Psychedelic control of neuroimmune interactions governing fear.
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
–field-weighted citation impact
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Who cites it
20 citing papers in PubMed.
- Article
- Psychedelics and astrocytes: a hypothesis-driven perspective on neuro-glial integration, network plasticity, and neuroimmune reprogramming.Molecular psychiatry · 2026Review
- VlPAG/DRN Microglia Drive Neuropathic Pain-Induced Depression via a Defined Neuroimmune Axis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Convergent neuroimmune signaling underlying rapid antidepressant response to ketamine and psychedelics.Molecular psychiatry · 2026Article
- Delayed astrocyte development impairs Sema6a-Plxna2/4-mediated astrocyte-neuron crosstalk and causes depressive-like behavior.Nature communications · 2026Article
- Brain-targeted epigenetic effects of two emerging psychoplastogens: ketamine & MDMA.Translational psychiatry · 2026Article
- Signaling Connectomics: A Brain-wide Framework for Intercellular Communication.Experimental neurobiology · 2026Article
- Circuit-informed modulation of traumatic memory in PTSD: integrating extinction, suppression, and reconsolidation.Molecular psychiatry · 2026Review
- Substance abuse and inflammation: consequences beyond the brain.Trends in immunology · 2026Review
- Article
- Astrocytes in predictive processing of emotion: Kir4.1 as precision modulator of social interaction.Acta pharmaceutica Sinica. B · 2026Article
- Pretreatment with the psychedelic DOI mitigates LPS-induced hippocampal inflammation and behavioral impairments in mice.BMC neuroscience · 2026Article
- Psychedelics elicit their effects by 5-HTNature · 2026Article
- Pilot study of psilocybin in patients with post-treatment lyme disease.Scientific reports · 2026Article
- Psychedelic therapy and postpartum depression: priorities and prospects.Therapeutic advances in psychopharmacology · 2026Review
- Connection and communication between the nervous and immune systems.Nature reviews. Immunology · 2025Review
- Integrative neuroimmunology reveals leukocyte-expressing PAX6 as a critical predictor of major depressive disorder.Translational psychiatry · 2025Article
- Review
- Can the gut-brain axis provide insight into psilocybin's therapeutic value in reducing stress?Neurobiology of stress · 2025Review
- Chloral Hydrate's Impact on Brain Development: From Clinical Safety to Molecular Mechanisms.Drug design, development and therapy · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors.
Elizabeth N Chung *The Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Jinsu Lee *The Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-7597-1560
Carolina M PolonioThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Joshua ChoiThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Camilo Faust AklThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-5883-4441
Michael KilianThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-1946-3174
Wiebke M WeißThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Georgia GunnerDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Mingyu YeDepartment of Neurology, Brigham and Women's Hospital and Jamaica Plain Veterans Administration Hospital, Harvard Medical School, Boston, MA, USA.
Tae Hyun HeoThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0009-0000-6817-4996
Sienna S DrakeThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Liu YangThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Catarina R G L d'EcaThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Joon-Hyuk LeeThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Liwen DengDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Daniel FarrenkopfThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Anton M SchüleThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0009-0003-3094-9778
Hong-Gyun LeeThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Oreoluwa AfolabiThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Sharmin GhaznaviDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-3773-9760
Stelios M SmirnakisDepartment of Neurology, Brigham and Women's Hospital and Jamaica Plain Veterans Administration Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-1929-2811
Isaac M ChiuDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-0723-4841
Vijay K KuchrooThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Francisco J QuintanaThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-8156-0736
Michael A WheelerThe Gene Lay Institute of Immunology and Inflammation, Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. mwheeler0@bwh.harvard.edu.ORCID 0000-0002-0689-6384
Funding
Staphylococcus aureus induced itch and neuro-immune signaling in skin infectionsR01AI168005 · NIAID · HARVARD MEDICAL SCHOOL · PI Isaac Ming-Cheng Chiu, ALEXANDER R HORSWILL · 2022 to 2026
$3.7MRole of a novel risk loci HAVCR2 of late-onset Alzheimer's disease in the regulation of microglial response in neurodegenerationR01AG080992 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI Oleg Butovsky, VIJAY K. KUCHROO · 2023 to 2026
$3.3MAHR-mediated immunosuppression in glioblastomaR01ES029136 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI Francisco J. Quintana, DAVID A REARDON · 2019 to 2026
$3.3MNeuroimmune interactions regulate development of allergic inflammationR01AI139536 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI KUCHROO, VIJAY K. · 2018 to 2022
$2.9MNociceptor neuron regulation of gastrointestinal barrier protection and host defenseR01DK127257 · NIDDK · HARVARD MEDICAL SCHOOL · PI CHIU, ISAAC MING-CHENG · 2021 to 2024
$2.2MControl of extracellular matrix remodeling by CD29+ astrocytesR01MH130458 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI Michael Alex Wheeler · 2022 to 2026
$2.1MRegulation of CNS AutoimmunityR01AI126880 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI QUINTANA, FRANCISCO J. · 2017 to 2021
$2.1MControl of Local CNS InflammationR01NS102807 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI QUINTANA, FRANCISCO J. · 2018 to 2022
$1.8MNeuroimmune interactions regulate development of allergic inflammationR37AI139536 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI VIJAY K. KUCHROO · 2024 to 2026
$1.8MA Psilocybin-Sensitive Neuroimmune Circuit Controlling Stress BehaviorsR01DA061199 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI Michael Alex Wheeler · 2024 to 2026
$1.7MControl of ETV1 transcriptional networks in amygdalar astrocytesR01MH132632 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI Michael Alex Wheeler · 2024 to 2026
$1.3MMolecular Control of Astrocytes in CNS InflammationR00NS114111 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI WHEELER, MICHAEL ALEX · 2023 to 2025
$783kNIAID NIH HHS R01 AI126880NIAID NIH HHS R01 AI139536NIAID NIH HHS R01 AI168005NIAID NIH HHS R37 AI139536NIA NIH HHS R01 AG080992NIDA NIH HHS R01 DA061199NIDDK NIH HHS R01 DK127257NIEHS NIH HHS R01 ES029136NIMH NIH HHS R01 MH130458NIMH NIH HHS R01 MH132632NINDS NIH HHS R00 NS114111NINDS NIH HHS R01 NS102807
Abstract
Neuroimmune interactions-signals transmitted between immune and brain cells-regulate many aspects of tissue physiology
Indexed as
FearHallucinogensNeuroimmunomodulationAmygdalaAnimalsAstrocytesErbB ReceptorsFemaleHumansMaleMiceMice, Inbred C57BLMonocytesNeuronsSignal TransductionStress, PsychologicalErbB ReceptorsHallucinogens
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.