Evidence map›Paper›PMID 40269132›Full record

Reviewnpj antimicrobials and resistance2025

Leveraging the microbiome to combat antibiotic resistant gynecological infections.

Tanya Kumar, Aryak Rekhi, Yumie Lee, Julielam Tran, Arlene Grace D Nagtalon, Sidhant Rohatgi, Erika L Cyphert

Abstract readReview
In one paragraph

Review in npj antimicrobials and resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tanya KumarUniversity of California San Diego, Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, USA.
Aryak RekhiUniversity of California San Diego, Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, USA.
Yumie LeeUniversity of California San Diego, Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, USA.
Julielam TranUniversity of California San Diego, Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, USA.
Arlene Grace D NagtalonUniversity of California San Diego, Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, USA.
Sidhant RohatgiUniversity of California San Diego, Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, USA.
Erika L CyphertUniversity of California San Diego, Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, USA. ecyphert@ucsd.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vaginal resistome can be considered a collection of the resistant determinants in the vaginal microbiome. Here we review the vaginal resistome including the microbes and resistant genes harbored in common gynecological infections, vaginal microbes that participate in horizontal gene transfer, host factors that contribute to the resistome, and common therapies. Finally, we provide perspective on technologies that can be leveraged to study the vaginal resistome and remaining challenges.

Identifiers

PMID40269132
PMCPMC12019171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.