Evidence map›Paper›PMID 40269125›Full record

ArticleScientific reports2025

Simultaneous production of fatty acids and amino polysaccharides from Norway spruce hydrolysates using oleaginous Mucor circinelloides.

Cristian Bolaño Losada, Francesca Di Bartolomeo, Alexander Wentzel, Sidsel Markussen, Simona Dzurendova, Boris Zimmermann, Kai Fjaer, Ondrej Slany, Anikó Várnai, Line Degn Hansen and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Cristian Bolaño LosadaFaculty of Science and Technology, Norwegian University of Life Sciences, Postbox 5003, 1432, Ås, Norway.
Francesca Di BartolomeoDepartment of Biotechnology and Nanomedicine, SINTEF Industry, 7465, Trondheim, Norway.
Alexander WentzelDepartment of Biotechnology and Nanomedicine, SINTEF Industry, 7465, Trondheim, Norway.
Sidsel MarkussenDepartment of Biotechnology and Nanomedicine, SINTEF Industry, 7465, Trondheim, Norway.
Simona DzurendovaFaculty of Science and Technology, Norwegian University of Life Sciences, Postbox 5003, 1432, Ås, Norway.
Boris ZimmermannFaculty of Science and Technology, Norwegian University of Life Sciences, Postbox 5003, 1432, Ås, Norway.
Kai FjaerFaculty of Science and Technology, Norwegian University of Life Sciences, Postbox 5003, 1432, Ås, Norway.
Ondrej SlanyFaculty of Science and Technology, Norwegian University of Life Sciences, Postbox 5003, 1432, Ås, Norway.
Anikó VárnaiFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences (NMBU), Christian Magnus Falsens vei 18, 1433, Ås, Norway.
Line Degn HansenFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences (NMBU), Christian Magnus Falsens vei 18, 1433, Ås, Norway.
Svein Jarle HornFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences (NMBU), Christian Magnus Falsens vei 18, 1433, Ås, Norway.
Vincent G H EijsinkFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences (NMBU), Christian Magnus Falsens vei 18, 1433, Ås, Norway.
Vishwanath PatilBorregaard AS, 1701, Sarpsborg, Norway.
Volha ShapavalFaculty of Science and Technology, Norwegian University of Life Sciences, Postbox 5003, 1432, Ås, Norway. Volha.shapaval@nmbu.no.

Funding

Norges Forskningsråd 257622
6 · The paper itself

Abstract

Lignocellulose is an abundant raw material and renewable carbon source for the production of single cell oils which can replace plant-derived oils in food, feed, fuels, and oleochemicals. Mucor circinelloides produces both fatty acids and amino polysaccharides, such as chitin and chitosan. This study evaluates hydrolysates of Norway spruce (Picea abies) as a carbon source for their simultaneous production. Cultivation in spruce hydrolysate media yielded 15.8 g/L of biomass, with fatty acids comprising ~ 50% of the cell dry weight and amino polysaccharides up to 8.5%. The fatty acid methyl ester (FAME) content and fatty acid profile were comparable to glucose fermentation. Optimal harvesting times ranged from 72 to 120 h, depending on desired yields. These findings demonstrate that Norway spruce hydrolysates are a viable and sustainable substrate for microbial lipid and polysaccharide production, supporting their potential use in biotechnology and industrial applications.

Indexed as

Fatty AcidsMucorPiceaPolysaccharidesBiomassFermentationHydrolysisFatty AcidsPolysaccharidesAmino polysaccharidesFatty acidsFermentationLignocelluloseMucor circinelloides

Identifiers

PMID40269125
PMCPMC12019349

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.