Evidence map›Paper›PMID 40269064›Full record

ArticleScientific reports2025

Dissolving microneedles fabricated from 3D-printed master molds for application in veterinary medicine.

Kornicka Justyna, Śniadek Patrycja, Marycz Krzysztof, Walczak Rafał

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kornicka JustynaDivision of Microsystems, Faculty of Electronics, Photonics and Microsystems, Wroclaw University of Science and Technology, 27 Wybrzeze Wyspianskiego Street, 50-370, Wrocław, Poland. justyna.kornicka@pwr.edu.pl.
Śniadek PatrycjaDivision of Microsystems, Faculty of Electronics, Photonics and Microsystems, Wroclaw University of Science and Technology, 27 Wybrzeze Wyspianskiego Street, 50-370, Wrocław, Poland.
Marycz KrzysztofInternational Institute of Translational Medicine, Jesionowa 11, 55-114, Malin, Poland.
Walczak RafałDivision of Microsystems, Faculty of Electronics, Photonics and Microsystems, Wroclaw University of Science and Technology, 27 Wybrzeze Wyspianskiego Street, 50-370, Wrocław, Poland.

Funding

Ministry of Science and Higher Education, Poland DWD/5/0305/2021
6 · The paper itself

Abstract

Microneedle (MN) technology is gaining popularity as it offers many benefits and advantages over the conventional drug delivery methods. The transdermal drug delivery system (TDDS) with MNs offers painless, precise, and easy-to-use solutions that can be obtained using cost-effective technologies such as 3D printing. Numerous examples of microneedle applications have been reported for human use, especially given the context of the recent pandemic and the development of vaccination technologies. However, there is limited exploration of microneedles in veterinary medicine. In the following work, we presented a proposal for the efficient production of quickly dissolving microneedle patches from PVP (polyvinylpyrrolidone) and PVA (polyvinyl alcohol) polymers based on a model microneedle array printed using DLP (Digital Light Processing) technology. We have developed a repeatable process in which the obtained microneedles can easily penetrate the outer layers of skin and quickly deliver the model drug. Such a versatile platform can be used, among others, in the treatment of animal gingival diseases, which affect a significant amount of the cat and dog population. An important advantage of the presented solution is the possibility of implementing the whole technological process in a veterinary office in a short time and the possibility of easy adjusting the size of the patches to a specific animal.

Indexed as

Drug Delivery SystemsMicroinjectionsNeedlesPrinting, Three-DimensionalVeterinary MedicineAdministration, CutaneousAnimalsCatsDogsPolyvinyl AlcoholPovidonePolyvinyl AlcoholPovidone3D printingDrug deliveryMicroneedleMicrosystemsVeterinary medicine

Identifiers

PMID40269064
PMCPMC12019400

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.