Evidence map›Paper›PMID 40269055›Full record

ArticleScientific reports2025

Synthesis, molecular docking, assessment of biological and anti-diabetic properties of benzalacetophenone derivatives.

Wesam S Shehab, Nourhan Kh R Elhoseni, Wael M Aboulthana, Mohamed G Assy, Sahar M Mousa, Gehan T El-Bassyouni

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wesam S ShehabDepartment of Chemistry, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt. dr.wesamshehab@gmail.com.
Nourhan Kh R ElhoseniDepartment of Chemistry, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
Wael M AboulthanaBiochemistry Department, National Research Centre, 33 El-Buhouth St., Dokki, Cairo, 12622, Egypt.
Mohamed G AssyDepartment of Chemistry, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
Sahar M MousaInorganic Chemistry Dept, National Research Centre, 33 El-Buhouth St., Dokki, Cairo, 12622, Egypt.
Gehan T El-BassyouniRefractories, Ceramics and Building Materials Department, National Research Centre, 33 El-Buhouth St., Dokki, Cairo, 12622, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current study compares the environmental impact of benzalacetophenone derivatives synthesized using conventional and nanomaterial-catalyzed techniques. Non-isolable thia-Michel adducts are produced when chalcone 1 reacts with thiourea thiolate anion; thiazine 2 is then obtained by cyclocondensation and dehydrogenation. Depending on the pH of the medium, hydrazine and target 1 can undergo pyrazole heterocyclization followed by N-acylation to produce compounds 3, 4, and 5. N-benzoylpyrazole derivative 6 was produced when compound 1 was allowed to condense with benzoylhydrazide. Hydroxylamine hydrochloride and chalcone 1 undergo cyclo-condensation, which releases H

Indexed as

Hypoglycemic AgentsMolecular Docking SimulationAcetophenonesAntioxidantsHumansAcetophenonesAntioxidantsHypoglycemic AgentsDiazapineMn3O4 nano particlePyrazolePyrazolineThiazine

Identifiers

PMID40269055
PMCPMC12019235

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.