Evidence map›Paper›PMID 40269052›Full record

Trial reportScientific reports2025

Time-course of muscle fatigue development during intense exercise in hypoxia and normoxia.

Jacob Bejder, Jonathan Graae, Jakob Boye Andersen, Ricardo Augusto Barbieri, Eduardo Zapaterra Campos, Jens Bangsbo, Lars Nybo, Nikolai Baastrup Nordsborg

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jacob BejderDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Nørre Allé 51, Copenhagen, 2200, Denmark.ORCID http://orcid.org/0000-0002-9698-9188
Jonathan GraaeDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Nørre Allé 51, Copenhagen, 2200, Denmark.ORCID http://orcid.org/0000-0002-0959-2706
Jakob Boye AndersenDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Nørre Allé 51, Copenhagen, 2200, Denmark.
Ricardo Augusto BarbieriDepartment of Life Quality Studies, University of Bologna, Rimini, Italy.ORCID http://orcid.org/0000-0003-3552-7585
Eduardo Zapaterra CamposGraduate Program in Physical Education, Federal University of Pernambuco, Recife, Brazil.ORCID http://orcid.org/0000-0002-9356-3683
Jens BangsboDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Nørre Allé 51, Copenhagen, 2200, Denmark.ORCID http://orcid.org/0000-0003-1305-9274
Lars NyboDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Nørre Allé 51, Copenhagen, 2200, Denmark.ORCID http://orcid.org/0000-0002-9090-1958
Nikolai Baastrup NordsborgDepartment of Nutrition, Exercise and Sports (NEXS), Faculty of Science, University of Copenhagen, Nørre Allé 51, Copenhagen, 2200, Denmark. nbn@nexs.ku.dk.ORCID http://orcid.org/0000-0001-7077-9265

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study is the first to determine how hypoxia affects human muscle fatigue kinetics and metabolic perturbations during intense dynamic exercise. Using randomized, single-blinded crossover designs, three trials of two-legged knee extensions were performed under hypoxic (HYP, FiO₂ 0.135) and normoxic (NOR) conditions. Trial 1 (n = 8): quadriceps femoris twitch force (F

Indexed as

ExerciseHypoxiaMuscle FatigueAdultCross-Over StudiesHumansHydrogen-Ion ConcentrationLactic AcidMaleMuscle ContractionMuscle, SkeletalYoung AdultLactic AcidExercise performanceHypoxemiaPeripheral muscle fatigue

Identifiers

PMID40269052
PMCPMC12018925

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.