Evidence map›Paper›PMID 40269046›Full record

ArticleScientific reports2025

Evaluating the performance of GPT-3.5, GPT-4, and GPT-4o in the Chinese National Medical Licensing Examination.

Dingyuan Luo, Mengke Liu, Runyuan Yu, Yulian Liu, Wenjun Jiang, Qi Fan, Naifeng Kuang, Qiang Gao, Tao Yin, Zuncheng Zheng

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Artificial Intelligence Literacy in Intensive Care: From Algorithmic Fluency to Clinical Accountability.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. [Application of large language models in health education for patients with pediatric cataract].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dingyuan Luo *Department of Rehabilitation Medicine Center, Affiliated Tai'an Central Hospital, Qingdao University, No. 29, Longtan Road, Taishan District, Tai'an City, 271000, Shandong, China.
Mengke Liu *Department of Radiology, Affiliated Shandong Provincial Hospital, Shandong First Medical University, Jinan, 250021, Shandong, China.
Runyuan Yu *Department of Rehabilitation Medicine Center, Affiliated Tai'an Central Hospital, Qingdao University, No. 29, Longtan Road, Taishan District, Tai'an City, 271000, Shandong, China.
Yulian LiuDepartment of Rehabilitation Medicine Center, Affiliated Tai'an Central Hospital, Qingdao University, No. 29, Longtan Road, Taishan District, Tai'an City, 271000, Shandong, China.
Wenjun JiangDepartment of Rehabilitation Medicine Center, Affiliated Tai'an Central Hospital, Qingdao University, No. 29, Longtan Road, Taishan District, Tai'an City, 271000, Shandong, China.
Qi FanDepartment of Rehabilitation Medicine Center, Affiliated Tai'an Central Hospital, Qingdao University, No. 29, Longtan Road, Taishan District, Tai'an City, 271000, Shandong, China.
Naifeng KuangDepartment of Rehabilitation Medicine Center, Affiliated Tai'an Central Hospital, Qingdao University, No. 29, Longtan Road, Taishan District, Tai'an City, 271000, Shandong, China.
Qiang GaoDepartment of Rehabilitation Medicine Center, Affiliated Tai'an Central Hospital, Qingdao University, No. 29, Longtan Road, Taishan District, Tai'an City, 271000, Shandong, China.
Tao YinDepartment of Rehabilitation Medicine Center, Affiliated Tai'an Central Hospital, Qingdao University, No. 29, Longtan Road, Taishan District, Tai'an City, 271000, Shandong, China. yintaokfk@163.com.
Zuncheng ZhengDepartment of Rehabilitation Medicine Center, Affiliated Tai'an Central Hospital, Qingdao University, No. 29, Longtan Road, Taishan District, Tai'an City, 271000, Shandong, China. zxyyzhengzuncheng@126.com.

Funding

Tai'an Science and Technology Innovation Development Project 2021NS358This research was funded by the National Clinical Key Specialty Construction Project and also supported by Shandong Province Medical and Health Science and Technology Development Programme 202120010262
6 · The paper itself

Abstract

This study aims to compare and evaluate the performance of GPT-3.5, GPT-4, and GPT-4o in the 2020 and 2021 Chinese National Medical Licensing Examination (NMLE), exploring their potential value in medical education and clinical applications. Six hundred original test questions from the 2020 and 2021 NMLE (covering five types of questions) were selected and input into GPT-3.5, GPT-4, and GPT-4o for response. The accuracy of the models across different question types and units was recorded and analyzed. Statistical methods were employed to compare the performance differences among the three models. GPT-4o demonstrated significantly higher overall accuracy than GPT-4 and GPT-3.5 (P < 0.001). In the 2020 and 2021 exams, GPT-4o achieved accuracy rates of 84.2% and 88.2%, respectively, with the highest accuracy observed in questions related to the digestive system (Unit 3), reaching 94.75%. GPT-4 showed moderate performance, while GPT - 3.5 had the lowest accuracy. Additionally, GPT-4o exhibited a clear advantage in complex question formats, such as case analysis questions (A3/A4 type) and standard matching questions (B1 type). GPT-4o outperformed its predecessors in the NMLE, demonstrating exceptional comprehension and problem-solving abilities in non-English medical examinations. This study provides important insights into the application and promotion of generative AI in medical education and clinical practice.

Indexed as

Educational MeasurementEducation, MedicalLicensure, MedicalChinaHumansArtificial intelligenceChatGPTLarge Language modelsMedical educationMedical licensing examination

Identifiers

PMID40269046
PMCPMC12018924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.