ArticleScientific reports2025
Effect of processing on microstructure, mechanical properties, corrosion and biocompatibility of additive manufacturing Ti-6Al-4V orthopaedic implants.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Characterization of Powder Bed Fusion-Laser Beam Ti6Al4V Samples in the As-Built and Stress-Relief States.Materials (Basel, Switzerland) · 2026Article
- Strength-ductility synergy in medium-entropy alloys via harnessing trace air in additive manufacturing.Nature communications · 2026Article
- Advancing Scoliosis Treatment with Patient-Specific Functionally Graded NiTi-SMA Rods: Key Considerations and Development Objectives.Bioengineering (Basel, Switzerland) · 2026Review
- Application of Laser and Cryogenic Surface Treatment for the Evolution of Surface Morphology in Additively Manufactured Ti-6Al-4V Alloy Samples.Materials (Basel, Switzerland) · 2025Article
- Metal Ion Release from PEO-Coated Ti6Al4V DMLS Alloy for Orthopedic Implants.Journal of functional biomaterials · 2025Article
- Effect of Heat Treatment on In Vitro Cytotoxicity of Ti-Nb-Zr Gum Metal Alloy.Materials (Basel, Switzerland) · 2025Article
- Laser-Driven Surface Alloying of Ti6Al4V: Coupled Microstructural Evolution, Phase Behavior, and Mechanical Performance.Materials (Basel, Switzerland) · 2025Article
- Article
- The Impact of As-Built Surface Characteristics of Selective-Laser-Melted Ti-6Al-4V on Early Osteoblastic Response for Potential Dental Applications.Journal of functional biomaterials · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study evaluates the microstructure, porosity, mechanical properties and corrosion resistance of Ti-6Al-4V hip implant samples manufactured by Selective Laser Melting (SLM) and Electron Beam Melting (EBM), followed by different post-treatments (heat treatment and hot isostatic pressing -HIP-). Hydroxyapatite (HA) coatings were applied to enhance biocompatibility. Post-treated samples exhibited a lamellar α + β microstructure, with the EBM sample showing a coarser Widmanstätten structure, while acicular α' martensite was predominant in the as-built sample. The degree of porosity was lower than 0.2% in all samples. Microhardness was highest in the as-built sample (~ 400 HV) and lower in post-treated samples (~ 370 HV). Open Circuit Potential (OCP) tests indicated superior corrosion resistance for heat-treated samples, confirmed by Electrochemical Impedance Spectroscopy (EIS), where Sample E-HIP (HIP) showed a polarization resistance (Rpol) of 2490 kΩ/cm². In vitro tests confirmed that HA-coated samples exhibited excellent biocompatibility, slightly surpassing the Ti-6Al-4V samples. The HA-coated samples exhibited increased metabolic activity over 7 days, indicating superior biocompatibility. Finally, additive manufacturing combined with heat treatments and HA coatings effectively enhances Ti-6Al-4V for orthopaedic implants by improving the mechanical performance, corrosion resistance and biocompatibility.
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