ArticleScientific reports2025
Ingesting chitosan can promote excretion of microplastics.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Micro- and nanoplastics in pediatric health: from placental transfer to neurodevelopmental outcomes.Pediatric research · 2026Review
- Reduction in Circulating Microplastics in Humans Following Gastrointestinal Sequestration by Chitosan: A Pilot Controlled Study.Journal of xenobiotics · 2026Article
- Microplastics and Nanoplastics in the Human Intestine: A Review of Health Implications and Possible Dietary Interventions.Advances in nutrition (Bethesda, Md.) · 2026Review
- Effect of different chitosan molecular weights on microplastic excretion.Frontiers in nutrition · 2026Article
- The Human Plastiphere: A Bioparticulate System Challenging Microplastic Risk Assessment and Governance.Environmental science & technology · 2025Review
- Preliminary Study on PCC-Chitosan's Ability to Enhance Microplastic Excretion in Human Stools from Healthy Volunteers.Foods (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, the presence of microplastics (MPs) in common foods such as salt and beverages has been widely reported Microplastics (MPs) have been widely reported in common foods, including salt and beverages. MPs spread through the food chain and are eventually ingested into the human body through the diet. They have been found to accumulate in human feces, blood, and liver tissues, raising concerns about the effects of continuous intake of foods containing MP on the body. We examined whether rats could rapidly excrete polyethylene MPs (average particle size of 200 μm) when the MPs and were mixed with non-digestive dietary materials in their feed (indigestible dextrin, lactosucrose, chitosan, and eggshell membrane proteins). The group that ingested chitosan showed significant changes, including increased fecal weight, increased MP excretion rate, and decreased intestinal MP retention rate. The MP excretion rates in feces 0-144 h after ingestion were 83.7% ± 3.8% in the control group and 115.6% ± 4.5% in the chitosan group. These findings indicate that chitosan effectively promotes the expulsion of polyethylene MPs. The addition of chitosan to food may reduce the potential harm caused by MPa to a variety of organisms, including humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.