Evidence map›Paper›PMID 40268948›Full record

ArticleScientific data2025

A Multi-Scale Neuron Morphometry Dataset from Peta-voxel Mouse Whole-Brain Images.

Shengdian Jiang, Sujun Zhao, Yingxin Li, Zhixi Yun, Lingli Zhang, Yufeng Liu, Hanchuan Peng

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shengdian JiangNew Cornerstone Science Laboratory, SEU-ALLEN Joint Center, Institute for Brain and Intelligence, Southeast University, Nanjing, Jiangsu, China.ORCID http://orcid.org/0000-0002-2277-263X
Sujun ZhaoNew Cornerstone Science Laboratory, SEU-ALLEN Joint Center, Institute for Brain and Intelligence, Southeast University, Nanjing, Jiangsu, China.ORCID http://orcid.org/0000-0001-7807-7495
Yingxin LiNew Cornerstone Science Laboratory, SEU-ALLEN Joint Center, Institute for Brain and Intelligence, Southeast University, Nanjing, Jiangsu, China.ORCID http://orcid.org/0009-0004-9399-0708
Zhixi YunNew Cornerstone Science Laboratory, SEU-ALLEN Joint Center, Institute for Brain and Intelligence, Southeast University, Nanjing, Jiangsu, China.ORCID http://orcid.org/0000-0002-8226-7408
Lingli ZhangNew Cornerstone Science Laboratory, SEU-ALLEN Joint Center, Institute for Brain and Intelligence, Southeast University, Nanjing, Jiangsu, China.
Yufeng LiuNew Cornerstone Science Laboratory, SEU-ALLEN Joint Center, Institute for Brain and Intelligence, Southeast University, Nanjing, Jiangsu, China. yufeng_liu@seu.edu.cn.ORCID http://orcid.org/0000-0003-0848-5113
Hanchuan PengNew Cornerstone Science Laboratory, SEU-ALLEN Joint Center, Institute for Brain and Intelligence, Southeast University, Nanjing, Jiangsu, China. h@braintell.org.ORCID http://orcid.org/0000-0002-3478-3942

Funding

Ministry of Science and Technology of the People's Republic of China (Chinese Ministry of Science and Technology) 2022ZD0205200/2022ZD0205204
6 · The paper itself

Abstract

Neuron morphology and sub-neuronal patterns offer vital insights into cell typing and the structural organization of brain networks. The community-collaborative BRAIN Initiative Cell Census Network (BICCN) project has yielded a vast amount of whole-brain imaging data. However, reconstructing multi-scale neuron morphometry at a whole-brain scale requires not only the integration of diverse hardware devices, tools, and algorithms but also a dedicated production workflow. To address these challenges, we developed a cloud-based, collaborative platform capable of handling peta-scale imaging data. Using this platform, we generated the largest multi-scale morphometry dataset from hundreds of sparsely labeled mouse brains. The morphometry dataset comprises 182,497 annotated cell bodies, 15,441 locally traced morphologies, and 1,876 fully reconstructed morphologies. We also identified sub-neuronal arborizations for both axons and dendrites, along with the primary axonal tracts connecting them. In addition, we identified 2.63 million putative boutons. All morphometric data were registered to the Allen Common Coordinate Framework (CCF) atlas. The morphometry dataset has proven to be an invaluable resource for whole-brain cross-scale morphological studies in mouse.

Indexed as

BrainNeuronsAnimalsMice

Identifiers

PMID40268948
PMCPMC12019545

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.