ArticleNature communications2025
Photon-counting Raman spectroscopy at a MHz spectral rate for biochemical imaging of an entire organism.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Vib2Mol: from vibrational spectra to molecular structures-a unified deep learning framework.Chemical science · 2026Article
- Raman Spectroscopy in Cancer Diagnostics and Surgery: 25 Years of Progress from Surface-Enhanced Raman Spectroscopy to Artificial Intelligence─A Bibliometric and Visualized Study.Analytical chemistry · 2026Review
- Label-free molecular profiling of cancer using Raman spectroscopy: from fundamentals to clinical applications.Frontiers in oncology · 2026Review
Corrections and comments
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Authors and funding
18 authors.
Funding
Abstract
Raman spectroscopy, which probes fine molecular vibrations, is crucial for interpreting covalent bonds, chemical compositions, and other molecular dynamics in mixtures via their vibrational fingerprint signatures. However, over the past few decades, longstanding barriers have been encountered in both the sensitivity and speed of Raman spectroscopy, limiting its ability to be extended to broader biochemical applications. Here, we introduce a versatile analytical workhorse, the fiber-array Raman engine (termed FIRE). In FIRE, a distinctive fiber array bundle delays the Raman shifts at a scale of 3-960 ns, and a highly dynamic single-channel photon-counting detector achieves spectral measurements that outperform the best commercial confocal Raman microscope. Crucially, FIRE features a major advantage of nonrepetitive single-shot spectra measurement at a MHz repetition rate with a full Raman span (-300-4300 cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.