ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2025
Association Between Carotid Intima-Media Thickness and Novel Lipid Parameters in Hypertensive Patients.
Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between atherogenic index of plasma and various metabolic conditions: an umbrella review on meta-analyses.BMC cardiovascular disorders · 2025Pooled it
- Atherogenic Index of Plasma as Predictor for Cardiovascular Events and Cardiometabolic Diseases:Findings from the PAMELA Study.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- An Assessment of the Paediatric Cardiovascular Risk Profile in San Nicola da Crissa, a Village in the Calabria Region (Southern Italy): A Cross-Sectional Study.Journal of cardiovascular development and disease · 2026Article
- The association between liver fibrosis markers and carotid atherosclerosis in non-alcoholic fatty liver disease is strongly influenced by age.BMC cardiovascular disorders · 2026Article
- Reliability of B-mode ultrasound measurement of carotid intima-media thickness in assessing cardiovascular risk: a cross-sectional study.Frontiers in cardiovascular medicine · 2026Article
- The association between hepatic fibrosis indicators and subclinical carotid atherosclerosis in the population with metabolic dysfunction-associated steatotic liver disease under 50 years old.Nutrition & metabolism · 2025Article
- Triglyceride-glucose index in the associations between chronic low-grade inflammation and carotid intima-media thickness: mediation and effect-modification across triglyceride-glucose strata.BMC cardiovascular disorders · 2025Article
- Association between the LDL/HDL ratio and sarcopenia in Chinese community-dwelling older adults.PloS one · 2025Article
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10 authors.
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Abstract
introductionCarotid Intima-Media Thickness (IMT) is a marker of subclinical atherosclerosis and cardiovascular risk. Dyslipidemia is a well-established risk factor for atherosclerosis and novel lipid parameters have recently emerged.
aimThe aim of our study was to assess the association between IMT and novel lipid parameters in hypertensive patients.
methodsWe analyzed the IMT of 848 hypertensive patients followed at the Hypertension Unit of San Gerardo Hospital (Monza, Italy). Classic (total, HDL, LDL and non-HDL cholesterol and triglycerides) and novel indices (non-HDL/HDL, LDL/HDL, total cholesterol/HDL, log triglycerides/HDL and triglycerides-glycemia index) were measured and calculated.
resultsUnivariable analyses showed a significant correlation between IMT and most lipid parameters. Multivariable linear regression with IMT as continuous dependent variable revealed a significant association with total cholesterol (β = 0.108, p = 0.001), LDL cholesterol (β = 0.119, p < 0.001), non-HDL cholesterol (β = 0.126, p < 0.001), non-HDL/HDL (β = 0.134, p < 0.001), LDL/HDL (β = 0.140, p < 0.001) and total cholesterol/HDL (β = 0.134, p < 0.001). Logistic multivariable regression with IMT categorized as ≥ or < 0.9 mm demonstrated a significant association with total cholesterol (OR = 1.100 per 10 mg/dL increase, p = 0.003), LDL cholesterol (OR = 1.130 per 10 mg/dL increase, p = 0.001), non-HDL cholesterol (OR = 1.110 per each unit increase, p = 0.001), non-HDL/HDL (OR = 1.368 per each unit increase, p = 0.002), LDL/HDL (OR = 1.583 per each unit increase, p = 0.001) and total cholesterol/HDL (OR = 1.368 per each unit increase, p = 0.002).
conclusionsCarotid IMT is significantly associated with various lipid parameters, with the strongest association observed for non-HDL/HDL, LDL/HDL and total cholesterol/HDL.
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