Evidence map›Paper›PMID 40268764›Full record

ReviewRadiologie (Heidelberg, Germany)2025

[Early-onset colorectal cancer : When should we start with screening?]

Michael Hoffmeister, Hermann Brenner

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Radiologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael HoffmeisterAbteilung Klinische Epidemiologie und Alternsforschung, Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Deutschland. m.hoffmeister@dkfz.de.
Hermann BrennerAbteilung Klinische Epidemiologie und Alternsforschung, Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn recent years, the number of new cases of colorectal cancer in people under the age of 50 (early-onset colorectal cancer, EOCRC) has increased, and extension of colorectal cancer screening for younger age groups is currently being discussed.

objectivesTo discuss whether the age for population-wide colorectal cancer screening should be lowered?

resultsExtension of population-wide screening to younger age groups particularly to those under the age of 40 would be highly inefficient due to the low colorectal cancer incidence. Still, it could be considered for people at increased risk, including young adults with familial risk. Implementation of primary prevention measures would already be possible.

conclusionsMore targeted risk-adapted prevention and screening strategies are needed to reverse the rising trend of EOCRC and to detect colorectal cancer more frequently at an early stage.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerMass ScreeningAdultAge of OnsetFemaleHumansIncidenceMaleMiddle AgedRisk FactorsEarly detection of cancerEpidemiologyPreventive carePrognosisRisk factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.