ArticleMedical physics2025
Characterization of commercial detectors for absolute proton UHDR dosimetry on a compact clinical proton synchrocyclotron.
Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Commissioning and Validation of a Synchrocyclotron - Based Ultra-High-Dose-Rate Beamline for FLASH.International journal of particle therapy · 2026Article
- Single-field-uniform-dose-per-fraction simultaneous dose and dose rate optimization (SFUDPF-SDDRO) method for proton FLASH therapy.Medical physics · 2026Article
- Experimental characterization of proton minibeam therapy delivery under FLASH dose-rate conditions.Scientific reports · 2026Article
- Advancing Proton Therapy: Integration of Minibeam Spatial Fractionation and FLASH Dose Rates.Research square · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundModern compact proton synchrocyclotrons can achieve ultra-high dose rates ( PURPOSE: In this work, we investigate the suitability of various commercial radiation detectors for accurate proton UHDR dosimetry using PBS proton beams from a compact proton synchrocyclotron (IBA ProteusONE). This is achieved by cross-calibrating them with conventional dose rates, measuring UHDR recombination (P
methodsAn IBA ProteusONE synchrocyclotron was initially tuned to achieve UHDRs with 228 MeV protons at 0° gantry angle. Various detectors, including Razor Chamber, Razor Nano Chamber, Razor Diode, and microDiamond, were cross-calibrated against a PPC05 plane-parallel ionization chamber (PPIC) that had an ADCL calibration coefficient of 59.23 cGy/nC. Then, all ionization chambers were exposed to UHDR protons with the P
resultsFaraday cup measurements were performed for a single spot proton UHDR beam, and the nozzle current at the isocenter was determined to be 129.5 nA during UHDR irradiations at 98.61% of the maximum theoretical dose rate. Repeated Faraday cup measurements of the UHDR beam yielded a percentage standard deviation of 0.8%, which was higher than 0.120% when similar repeated measurements were performed with conventional proton beams. P
conclusionIn this work, we comprehensively evaluated the suitability of various commercial detectors for absolute dosimetry with a pulsed UHDR beam structure from a proton synchrocyclotron. PPC05 had the lowest ionic recombination correction compared to Razor and Razor Nano ion chambers. Other than the diode detector, all other investigated detectors (PPC05, Razor, Razor Nano, microDiamond) were within ± 1% of one another and can be used for accurate absolute proton UHDR dosimetry.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.