ArticleTrends in parasitology2025
Holding hands to halt malaria: stronger together through heterotypic antibody interactions.
Article in Trends in parasitology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
Abstract
Erythrocyte invasion by the malaria-causing parasite Plasmodium falciparum can be inhibited by antibodies against apical membrane antigen 1 (AMA1). Patel et al. identified two human anti-AMA1 monoclonal antibodies, one of which has strain-transcending neutralizing activity. Lateral interactions between the two antibodies improved their binding kinetics and inhibitory activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.