Evidence map›Paper›PMID 40268494›Full record

ArticleInternational journal of spine surgery2026

A Spine Surgeon's Learning Curve With the Minimally Invasive L5 to S1 Lateral ALIF Surgical Approach: Perioperative Outcomes and Technical Considerations.

Martin H Pham, Alexander J Schupper, Brian R Hirshman, Timothy Y Kim

Abstract read
In one paragraph

Article in International journal of spine surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Martin H PhamDepartment of Neurosurgery, University of California San Diego School of Medicine, San Diego, CA, USA.
Alexander J SchupperDepartment of Neurosurgery, Mount Sinai Icahn School of Medicine, New York, NY, USA.
Brian R HirshmanDepartment of Neurosurgery, University of California San Diego School of Medicine, San Diego, CA, USA.
Timothy Y KimDepartment of Neurosurgery, University of California San Diego School of Medicine, San Diego, CA, USA tyk004@health.ucsd.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLateral anterior lumbar interbody fusion (L-ALIF), or oblique lumbar interbody fusion at L5 to S1 (OLIF51), is a minimally invasive approach between the iliac vessels that provide indirect decompression, alignment restoration, and lordosis. While supine ALIF exposure has historically been performed by vascular surgeons, minimally invasive L-ALIF can be performed by spine surgeons familiar with lateral approaches. The L-ALIF is a relatively newer approach, and the objective of the present study was to assess the learning curve of the L-ALIF approach by comparing the pre- and postoperative radiographic measurements, patient-reported outcome measures (PROMs), and complications in a surgeon's first 25 L-ALIF patients compared with the subsequent 25 L-ALIF patients.

methodsThis retrospective case series includes the first 50 OLIF patients at/or including L5 to S1 by 1 surgeon. Demographics, complications, PROMs, and clinical and radiographic results were collected, and patients were analyzed comparing the surgeon's first 1 to 25 patients (group A) and last 26 to 50 patients (B).

resultsDemographic analysis demonstrated a mean age of 59.7 years and a body mass index of 28.7, and 52% of participants were women. The diagnosis was degenerative disc disease in 36 patients and deformity in 14 patients. Fourteen patients underwent single interbody level fusions at L5 to S1, 21 with 2 levels, and 15 with 3 to 6 levels. Segmental L5 to S1 lordosis increased 9.6° ± 3.9°, final mean lordosis 25.3° ± 8.3°; L5 to S1 disc angle increased 11.5° ± 4.9°, final disc angle 19.7° ± 3.8°; posterior disc height increased 3.6 mm ± 2.1 mm with final mean disc height 7.6 mm ± 1.8 mm. PROMs postoperatively were significantly improved from preoperatively. There were no significant differences in operative times for degenerative 1- or 2-level single-position surgery operations between groups A and B. Two group A patients had incisional hernias requiring repair, and 2 group B patients had postoperative ileus. There were no approach-related injuries.

conclusionWith proper patient selection and meticulous technique, the minimally invasive L-ALIF at L5 to S1 can be performed by surgeons experienced with lateral approaches to other spine levels. This study provides level 4 evidence and low-quality evidence in the Grading of Recommendations Assessment, Development, and Evaluation framework. CLINICAL RELEVANCE: The lateral ALIF is a safe and effective approach at L5 to S1 for spine surgeons and provides good clinical, biomechanical, and radiographic outcomes, especially for those who do not have access surgeons available. Close attention to left common iliac vein anatomy is paramount for this type of approach and similar to other approaches. With increased repetition and numbers of cases, surgeons are able to improve in their technique. LEVEL OF EVIDENCE: 4:

Indexed as

L5-S1 interbody fusionlateral ALIFminimally invasive spine surgeryOLIFsurgical technique

Identifiers

PMID40268494
PMCPMC13393919

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.