Evidence map›Paper›PMID 40268482›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

The Anterior Insula Processes a Time-Resolved Subjective Risk Prediction Error.

Jae-Chang Kim, Lydia Hellrung, Stephan Nebe, Philippe N Tobler

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jae-Chang KimZurich Center for Neuroeconomics, Department of Economics, University of Zurich, Zurich 8006, Switzerland jaechang.kim@econ.uzh.ch phil.tobler@econ.uzh.ch.ORCID 0000-0001-5224-817X
Lydia HellrungZurich Center for Neuroeconomics, Department of Economics, University of Zurich, Zurich 8006, Switzerland.
Stephan NebeZurich Center for Neuroeconomics, Department of Economics, University of Zurich, Zurich 8006, Switzerland.
Philippe N ToblerZurich Center for Neuroeconomics, Department of Economics, University of Zurich, Zurich 8006, Switzerland jaechang.kim@econ.uzh.ch phil.tobler@econ.uzh.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The insula processes errors in the prediction of risky, motivationally relevant outcomes and thereby is thought to respond similarly to better-than-predicted and worse-than-predicted outcomes. However, the nature of the encoded risk prediction error signals remained unclear. Moreover, the insula was proposed to preferentially process events and stimuli in the aversive domain, rather than in a domain-general fashion. Here, we aimed to illuminate these issues. In a Pavlovian task, participants (

Indexed as

Insular CortexRisk-TakingAdolescentAdultBrain MappingConditioning, ClassicalCuesFemaleHumansMagnetic Resonance ImagingMaleTime FactorsYoung Adultattentionlearninguncertainty

Identifiers

PMID40268482
PMCPMC12139582

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.