ArticleRespiratory medicine2025
Elevated risk of dyspnea in pediatric patients three months after pulmonary embolism.
Article in Respiratory medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07576478 (Effects of Blowing Balloon Therapy on Pulmonary Function, Dyspnea and Quality of Life in Obese Children), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Blowing Balloon Therapy on Pulmonary Function, Dyspnea and Quality of Life in Obese Children
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Authors and funding
6 authors.
Funding
Abstract
This study investigated whether pediatric patients with a prior pulmonary embolism (PE) are more likely to have a diagnosis of dyspnea compared with those who have not had a PE. We obtained de-identified data from TriNetX, using both UT Southwestern (UTSW) and Research Networks, and identified patients aged 8-21 years with a diagnosis of PE (ICD-10-CM I26) and dyspnea (ICD-10-CM R06.0). Patients with a PE diagnosis had a significantly higher risk for a diagnosis of dyspnea. This relationship was observed in both the UTSW Network (OR 4.57 [95 % CI 2.82-7.43]; p < 0.0001) and Research Network (OR 6.57 [95 % CI 5.65-7.65]; p < 0.0001). Moreover, the risk of having a dyspnea diagnosis was significantly higher for females compared with males with a PE diagnosis in Research Networks (p < 0.0001). These findings have significant clinical implications, suggesting that clinicians should consider prior PE as an independent risk factor for diagnosis of dyspnea in pediatric patients after excluding other possible contributing factors.
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