Evidence map›Paper›PMID 40267695›Full record

ArticleMultiple sclerosis and related disorders2025

The unmet need for cannabis use disorder treatment in multiple sclerosis: Insights from a nationwide pilot study.

Giuseppina Pilloni, Shayna Pehel, Timothy Ko, Erica Kreisberg, Carrie Sammarco, R Erik Charlson, Leigh Charvet

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Multiple sclerosis and related disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giuseppina PilloniNew York University Grossman School of Medicine, Department of Neurology, 222 East 41st Street, 10th Floor, New York, NY 10017, USA.
Shayna PehelNew York University Grossman School of Medicine, Department of Neurology, 222 East 41st Street, 10th Floor, New York, NY 10017, USA.
Timothy KoNew York University Grossman School of Medicine, Department of Neurology, 222 East 41st Street, 10th Floor, New York, NY 10017, USA.
Erica KreisbergNew York University Grossman School of Medicine, Department of Neurology, 222 East 41st Street, 10th Floor, New York, NY 10017, USA.
Carrie SammarcoNew York University Grossman School of Medicine, Department of Neurology, 222 East 41st Street, 10th Floor, New York, NY 10017, USA.
R Erik CharlsonNew York University Grossman School of Medicine, Department of Neurology, 222 East 41st Street, 10th Floor, New York, NY 10017, USA.
Leigh CharvetNew York University Grossman School of Medicine, Department of Neurology, 222 East 41st Street, 10th Floor, New York, NY 10017, USA. Electronic address: leigh.charvet@nyulangone.org.

Funding

A telehealth tDCS approach to decrease cannabis use: Towards reducing multiple sclerosis disability in multiple sclerosisR21DA055427 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHARVET, LEIGH, PILLONI, GIUSEPPINA · 2022 to 2023
$466k
NIDA NIH HHS R21 DA055427
6 · The paper itself

Abstract

More than half of individuals with multiple sclerosis (MS) use cannabis, with up to 20 % at risk of cannabis use disorder (CUD). While some individuals with MS report symptom relief from cannabis use, particularly for pain, sleep, and mood, there is limited support for its evidence-based therapeutic use. In contrast, long-term use has been associated with poorer cognitive and emotional functioning, fatigue, and reduced quality of life. Although reducing or stopping cannabis use has shown benefits, there is a lack of accessible interventions. We recruited nationally for a pilot study of a remotely supervised home-based intervention to reduce cannabis use among women with MS and CUD. The trial response provided critical insights into cannabis use patterns and the significant demand for accessible, effective interventions, highlighting an urgent unmet need within the MS community.

Indexed as

Marijuana AbuseMultiple SclerosisAdultFemaleHumansMiddle AgedPilot ProjectsCannabisMultiple sclerosisSubstance use disorderSymptom managementTelehealth

Identifiers

PMID40267695
PMCPMC12179776

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.