Evidence map›Paper›PMID 40267503›Full record

ArticleJMIR aging2025

Association Between Sleep Duration and Cognitive Frailty in Older Chinese Adults: Prospective Cohort Study.

Ruixue Cai, Jianqian Chao, Chenlu Gao, Lei Gao, Kun Hu, Peng Li

Abstract read
In one paragraph

Article in JMIR aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruixue CaiDepartment of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, China.ORCID http://orcid.org/0000-0001-8641-0753
Jianqian ChaoDepartment of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, China.ORCID http://orcid.org/0009-0002-3635-070X
Chenlu GaoDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 149 13th Street, Boston, MA, 02129, United States, 1 6176516591.ORCID http://orcid.org/0000-0001-7162-8303
Lei GaoDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 149 13th Street, Boston, MA, 02129, United States, 1 6176516591.ORCID http://orcid.org/0000-0003-1476-1460
Kun HuDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 149 13th Street, Boston, MA, 02129, United States, 1 6176516591.ORCID http://orcid.org/0000-0003-0350-3132
Peng LiDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 149 13th Street, Boston, MA, 02129, United States, 1 6176516591.ORCID http://orcid.org/0000-0002-4684-4909

Funding

Integrative Motor Activity Biomarker for the Risk of Alzheimer's RiskRF1AG064312 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, KUN · 2019 to 2019
$3.6M
Circadian Disturbance and Dementia in Latin AmericaR01AG083799 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Kun Hu, Agustin M. Ibanez · 2023 to 2026
$3.0M
NIA NIH HHS R01 AG083799NIA NIH HHS RF1 AG064312
6 · The paper itself

Abstract

Background: Disturbed sleep patterns are common among older adults and may contribute to cognitive and physical declines. However, evidence for the relationship between sleep duration and cognitive frailty, a concept combining physical frailty and cognitive impairment in older adults, is lacking. Objective: This study aimed to examine the associations of sleep duration and its changes with cognitive frailty. Methods: We analyzed data from the 2008-2018 waves of the Chinese Longitudinal Healthy Longevity Survey. Cognitive frailty was rendered based on the modified Fried frailty phenotype and Mini-Mental State Examination. Sleep duration was categorized as short (<6 h), moderate (6-9 h), and long (>9 h). We examined the association of sleep duration with cognitive frailty status at baseline using logistic regressions and with the future incidence of cognitive frailty using Cox proportional hazards models. Restricted cubic splines were used to explore potential nonlinear associations. Results: Among 11,303 participants, 1298 (11.5%) had cognitive frailty at baseline. Compared to participants who had moderate sleep duration, the odds of having cognitive frailty were higher in those with long sleep duration (odds ratio 1.71, 95% CI 1.48-1.97; P<.001). A J-shaped association between sleep duration and cognitive frailty was also observed (P<.001). Additionally, during a mean follow-up of 6.7 (SD 2.6) years among 5201 participants who were not cognitively frail at baseline, 521 (10%) participants developed cognitive frailty. A higher risk of cognitive frailty was observed in participants with long sleep duration (hazard ratio 1.32, 95% CI 1.07-1.62; P=.008). Conclusions: Long sleep duration was associated with cognitive frailly in older Chinese adults. These findings provide insights into the relationship between sleep duration and cognitive frailty, with potential implications for public health policies and clinical practice.

Indexed as

Cognitive DysfunctionFrail ElderlyFrailtySleepAgedAged, 80 and overChinaFemaleHumansLongitudinal StudiesMaleProspective StudiesRisk FactorsSleep DurationTime Factorsagingcognitioncohort studyfrailtylongitudinal studysleep durationsleep quality

Identifiers

PMID40267503
PMCPMC12043274

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.