Evidence map›Paper›PMID 40267307›Full record

ArticleAge and ageing2025

Low gait speed is better than frailty and sarcopenia at identifying the risk of disability in older adults.

Aline Fernanda de Souza, Dayane Capra de Oliveira, Paula Camila Ramírez, Roberta de Oliveira Máximo, Mariane Marques Luiz, Maicon Luís Bicigo Delinocente, Andrew Steptoe, Cesar de Oliveira, Tiago da Silva Alexandre

Abstract readComparative Study
In one paragraph

Article in Age and ageing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Frailty phenotype in adults with sickle cell disease.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  6. Whose health matters? Longitudinal analyses of older romantic couples' health, physical capabilities, and sexual experiences.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aline Fernanda de SouzaDepartment of Physical Therapy, Postgraduate Program in Physical Therapy, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil.
Dayane Capra de OliveiraDepartment of Physical Therapy, Postgraduate Program in Physical Therapy, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil.ORCID 0000-0001-9757-9458
Paula Camila RamírezFacultad de Salud, Escuela de Fisioterapia, Universidad Industrial de Santander, Bucaramanga, Colombia.
Roberta de Oliveira MáximoDepartment of Gerontology, Postgraduate Program in Gerontology, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil.
Mariane Marques LuizDepartment of Physical Therapy, Postgraduate Program in Physical Therapy, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil.ORCID 0000-0001-5563-6354
Maicon Luís Bicigo DelinocenteDepartment of Gerontology, Postgraduate Program in Gerontology, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil.
Andrew SteptoeDepartment of Behavioural Science and Health, University College London, London, UK.ORCID 0000-0001-7808-4943
Cesar de OliveiraDepartment of Epidemiology and Public Health, University College London, London, UK.ORCID 0000-0002-4099-4762
Tiago da Silva AlexandreDepartment of Physical Therapy, Postgraduate Program in Physical Therapy, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil.ORCID 0000-0003-3791-9793

Funding

Project-001R01AG017644 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI Andrew Steptoe · 2000 to 2026
$56.2M
Brazilian National Council for Scientific and Technological DevelopmentCoordination for the Advancement of Higher Education Personnel 305,338/2023-4Economic and Social Research Council ES/T008822/11National Institute on Ageing of the National Institutes of Health 303577/2020-7NIA NIH HHS R01 AG017644NIHR Policy Research Programme 98_1074_03Sao Paulo Research Foundation support Tiago da Silva Alexandre 2018/13917-3
6 · The paper itself

Abstract

objectiveTo compare frailty, sarcopenia and their respective components to determine which is more effective in identifying the risk of disability in basic and instrumental activities of daily living (BADL and IADL, respectively).

methodsA longitudinal study involving 3,637 individuals without disabilities concerning BADL and 3,696 individuals without disabilities regarding IADL at baseline. Frailty was defined using the phenotype. Sarcopenia was determined according to the criteria proposed by the EWGSOP2: low strength (grip strength <27 kg for men and <16 kg for women), low skeletal muscle mass index (<9.36 kg/m2 for men and <6.73 kg/m2 for women) and low physical performance (gait speed ≤0.8 m/s). In addition to the complete constructs, each component was assessed. Poisson mixed models were utilised, with the outcome identified as incident cases of disability over 8 years, adjusted for covariates. Results: Pre-frailty was associated with a 17% and 18% annual increase in the risk of disability for BADL and IADL, respectively. These figures were 27% and 28% for individuals classified as frail. Sarcopenia was not associated with an increased risk of disability. Amongst the components of frailty and sarcopenia, low physical performance, assessed by gait speed ≤0.8 m/s, was the most effective for identifying the risk of disability (12% per year for BADL and 14% per year for IADL).

conclusionIn clinical practice, low physical performance (gait speed ≤0.8 m/s) may be the preferred tool for screening the risk of functional decline in older adults.

Indexed as

Disability EvaluationFrail ElderlyFrailtyGeriatric AssessmentSarcopeniaWalking SpeedActivities of Daily LivingAgedAged, 80 and overAge FactorsFemaleHand StrengthHumansLongitudinal StudiesMalePredictive Value of Testsfrail older peoplegait speedolder peoplesarcopenic older peopleslowness

Identifiers

PMID40267307
PMCPMC12017394

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.