ArticlePloS one2025
Predictors of complications following alloplastic cranioplasty in trauma patients: A multi-center retrospective study.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Material type versus defect size in adult cranioplasty: a multi-institutional analysis of 30-day outcomes and risk prediction modeling.JPRAS open · 2026Article
- Reduced Temporal Muscle Thickness Is Associated with Increased Postoperative Complications After Cranioplasty.Journal of clinical medicine · 2026Article
- The timing of cranioplasty and the risk of postoperative complications: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Secondary decompressive craniectomy after severe traumatic brain injury: a retrospective cohort study.Frontiers in neurology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectAlthough technically simple, cranioplasty following decompressive craniectomy is associated with high complication rates. Assessing the factors that contribute to these complications is essential. The study aimed to present the complications following alloplastic cranioplasty in trauma patients and evaluate the factors that predispose patients to an increased risk of complications.
methodsThe author retrospectively reviewed cranioplasty cases at three institutions following craniectomy for trauma between 01/01/2018 and 31/12/2021. The risk factors included age, sex, smoking history, defect site, defect size, type of alloplastic materials, hydrocephalus after decompressive craniectomy (DC), hydrocephalus shunts before cranioplasty (CP), and the time interval between initial craniectomy and cranioplasty. The cranioplasty complications assessed were postoperative new-onset seizures, reoperation for hematoma, implant failure, and postoperative subgaleal effusion. Multivariate logistic regression analysis was performed to assess these risk factors.
resultsA total of 191 cranioplasties were included in this study, with a major complication rate of 26.2% (50 of 191). In multivariate analysis, the risk factors for major complications were smoking history, titanium cranioplasty, and a time interval to cranioplasty exceeding 3 months. Predictors of new-onset seizures in multivariate analysis included younger age, smoking history (OR = 4.69, p < 0.001), titanium cranioplasty (OR = 4.85, p = 0.049), and intermediate CP (OR = 5.46, p = 0.042). The rates of implant failure and postoperative hematoma were higher when cranioplasty was performed over 3 months or involved titanium cranioplasty. The rate of minor complication, specifically subgaleal effusion, was 18.9% (36 cases), with male sex being a significant variable in multivariate analysis.
conclusionsThis study presented complications and predictors of complications for cranioplasty in trauma patients, which could be incorporated with surgical decision-making for neurosurgeons.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.