Evidence map›Paper›PMID 40266475›Full record

ArticleUpdates in surgery2025

The use of thyroid cartilage needle electrodes during intra-operative nerve monitoring in thyroid surgery: A multi-center retrospective study.

Kaan Balcı, Yiğit Türk, Murat Özdemir, Paulina Kuczma, Christophe Tresallet, Che-Wei Wu, Tzu-Yen Huang, Adi Syazni Muhammed, Rohaizak Muhammad, Shahrun Niza Bin Abdullah Suhaimi and 5 more

Abstract readMulticenter Study
In one paragraph

Article in Updates in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Balancing hemostasis and function: the impact of hemostatic materials on voice and swallowing outcomes in nerve-preserved thyroidectomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kaan BalcıDepartment of General Surgery, Division of Endocrine Surgery, Ege University Hospital, Izmir, Turkey.
Yiğit TürkDepartment of General Surgery, Division of Endocrine Surgery, Ege University Hospital, Izmir, Turkey.
Murat ÖzdemirDepartment of General Surgery, Division of Endocrine Surgery, Ege University Hospital, Izmir, Turkey.
Paulina KuczmaDepartment of Digestive, Bariatric and Endocrine Surgery, Avicenne University Hospital, Sorbonne Paris Nord University, Assistance Publique-Hôpitaux de Paris, Bobigny, France.
Christophe TresalletDepartment of Digestive, Bariatric and Endocrine Surgery, Avicenne University Hospital, Sorbonne Paris Nord University, Assistance Publique-Hôpitaux de Paris, Bobigny, France.
Che-Wei WuDepartment of Otolaryngology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Tzu-Yen HuangDepartment of Otolaryngology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Adi Syazni MuhammedBreast & Endocrine Surgery Unit, Department of Surgery, Hospital Canselor Tuanku Muhriz UKM, Kuala Lumpur, Malaysia.
Rohaizak MuhammadBreast & Endocrine Surgery Unit, Department of Surgery, Hospital Canselor Tuanku Muhriz UKM, Kuala Lumpur, Malaysia.
Shahrun Niza Bin Abdullah SuhaimiBreast & Endocrine Surgery Unit, Department of Surgery, Hospital Canselor Tuanku Muhriz UKM, Kuala Lumpur, Malaysia.
Nani HarlinaBreast & Endocrine Surgery Unit, Department of Surgery, Hospital Canselor Tuanku Muhriz UKM, Kuala Lumpur, Malaysia.
Matija BuzejicClinic for Endocrine Surgery, University Clinical Center of Serbia, Belgrade, Serbia.
Vladan ZivaljevicClinic for Endocrine Surgery, University Clinical Center of Serbia, Belgrade, Serbia.
Milan JovanovicClinic for Endocrine Surgery, University Clinical Center of Serbia, Belgrade, Serbia.
Özer MakayCenter of Endocrine Surgery, Ozel Saglik Hospital, Izmir, Turkey. makayozer@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In previous studies, the use of thyroid cartilage needle electrodes (TCN) was defined as an inexpensive method for intra-operative nerve monitoring (IONM) in thyroid surgery. This multi-center retrospective study aims to determine the effectiveness and reliability of TCN in thyroid surgery. Patients operated on between January 2018 and August 2023 from five centers were included in this study. Demographic data, indications, type of surgery, IONM recording system, pre-post-resection vagus nerve (V1-V2), pre-post-resection recurrent laryngeal nerve (R1-R2) amplitudes and latency values, type of loss of signal (LOS), adverse event (AE), intra-operative injury mechanism, and post-operative vocal cord examination (VCE) were evaluated. Patients with abnormal preoperative vocal cord examination were excluded. A total of 2105 patients (3772 nerves at risk) were included [1626 (77%) female, 479 (23%) male]; within this study, 1112 patients (53%) received a diagnosis of malignancy, while 993 (47%) were diagnosed with benign conditions. The mean initial vagus amplitude was 1093.74 µV (± 861.39). LOS occurred in 63 patients [Type 1 (84%), Type 2 (16%)] and AE in 36. No false-positive LOS occurred. Forty-six (87%) of LOS type 1 patients and nine (90%) of LOS type 2 patients had vocal cord palsy (VCP) during VCE (p < 0.05). In AE patients, there were only two (5.5%) patients who had vocal cord palsy during VCE (p < 0.05). VCP occurred in 57(2.7%) patients, with 9 (0.42%) remaining permanent. TCN is an inexpensive and feasible alternative to endotracheal tube electrodes and a system with satisfying amplitudes. It can also precisely predict post-operative vocal cord functions.

Indexed as

Intraoperative Neurophysiological MonitoringMonitoring, IntraoperativeThyroid CartilageThyroidectomyThyroid GlandAdultAgedElectrodesFemaleHumansMaleMiddle AgedNeedlesRecurrent Laryngeal NerveRecurrent Laryngeal Nerve InjuriesReproducibility of ResultsAdverse eventIntraoperative nerve monitoringLoss of signalRecurrent laryngeal nerveThyroid cartilage needle electrodes

Identifiers

PMID40266475
PMCPMC12263753

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.