Evidence map›Paper›PMID 40266423›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

MOG antibody-positive patients meeting diagnostic criteria for MS: is it MOGAD with an MS-like phenotype or true MS?

Hung Youl Seok

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. AChR-blocking antibodies and complement system dynamics: evaluating their interplay and clinical implications in myasthenia gravis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Hung Youl SeokDepartment of Neurology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, 130 Dongdeok-ro, Jung-gu, Daegu, 41944, Republic of Korea. shy2354@gmail.com.ORCID http://orcid.org/0000-0002-9938-5355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is a recently recognized disorder distinct from multiple sclerosis (MS) and neuromyelitis optica spectrum disorder. The introduction of diagnostic criteria for MOGAD in 2023 marked a significant advance, providing high diagnostic accuracy for typical cases. However, challenges arise when patients test positive for MOG antibodies while also meeting the 2017 McDonald criteria for MS. These cases present a diagnostic dilemma, as they blur the lines between MS and MOGAD, complicating treatment decisions. This review addresses the diagnostic and management challenges faced by these patients, highlighting recent studies that underscore the difficulty in distinguishing between these two diseases and offering insights into how to approach these ambiguous cases.

Indexed as

AutoantibodiesMultiple SclerosisMyelin Oligodendrocyte Glycoprotein Antibody-Associated DiseaseNeuromyelitis OpticaDiagnosis, DifferentialHumansMyelin-Oligodendrocyte GlycoproteinPhenotypeAutoantibodiesMOG protein, humanMyelin-Oligodendrocyte GlycoproteinDiagnostic challengesMultiple sclerosisMyelin oligodendrocyte glycoprotein antibody-associated diseaseOligoclonal bands

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.