Evidence map›Paper›PMID 40266344›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2026

Unraveling the complex relationships between anxiety, depression, and quality of life in schizophrenia: a network analysis study.

Peiyi Wu, Yucheng Wang, Yang Zhou, Yixiao Xu, Huanrui Zhang, Zijia Li, Yanqing Tang

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Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peiyi Wu *Department of Psychiatry, Shengjing Hospital of China Medical University, 155 Nanjing North Street, Shenyang, 114000, Liaoning, China.
Yucheng Wang *Department of Psychiatry, Shengjing Hospital of China Medical University, 155 Nanjing North Street, Shenyang, 114000, Liaoning, China.
Yang ZhouDepartment of Epidemiology and Biostatistics, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, Beijing, China.
Yixiao XuDepartment of Psychiatry, The First Hospital of China Medical University, Shenyang, China.
Huanrui ZhangDepartment of Geriatrics, The First Hospital of China Medical University, Shenyang, China.
Zijia LiDepartment of Psychiatry, Shengjing Hospital of China Medical University, 155 Nanjing North Street, Shenyang, 114000, Liaoning, China.
Yanqing TangDepartment of Psychiatry, Shengjing Hospital of China Medical University, 155 Nanjing North Street, Shenyang, 114000, Liaoning, China. tangyanqing@cmu.edu.cn.ORCID http://orcid.org/0000-0002-1331-4936

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study utilized network analysis to explore the intricate relationships between anxiety, depression, and quality of life in a cohort of hospitalized schizophrenia patients. Through a cross-sectional design, the investigation aimed to identify key symptoms and bridge connections to inform tailored clinical interventions and improve patient well-being. Symptom severity was measured using the Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, and Schizophrenia Quality of Life Scale, with network analysis elucidating central nodes and bridging symptoms within the patient sample of 1328 individuals. Findings revealed psychic anxiety, insomnia, and depressed mood as pivotal within the network, significantly impacting overall symptomatology and quality of life. Furthermore, symptoms such as tension and fears were identified as essential connectors among different symptom domains, highlighting potential intervention targets. The study underscores the complex dynamics between anxiety, depression, and quality of life in schizophrenia, advocating for an integrated treatment approach that focuses on critical symptoms to enhance overall well-being. This approach suggests a paradigm shift towards personalized care in schizophrenia management, aiming to optimize outcomes by addressing the root of symptom networks.

Indexed as

AnxietyDepressionQuality of LifeSchizophreniaSchizophrenic PsychologyAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedAnxietyDepressionIndividualized interventionsNetwork analysisQuality of lifeSchizophrenia

Identifiers

PMID40266344

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.