Evidence map›Paper›PMID 40266312›Full record

ArticleInternational orthopaedics2025

Lateral closing wedge high tibial osteotomy procedure for the treatment of medial knee osteoarthritis: eleven years mean follow up analysis.

Giacomo Dal Fabbro, Giovanni Balboni, Stefano Di Paolo, Giorgio Varchetta, Alberto Grassi, Giulio Maria Marcheggiani Muccioli, Stefano Zaffagnini

Abstract read
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Article in International orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. The ageing meniscus: Pathophysiology, epidemiology and management.Journal of experimental orthopaedics · 2026
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giacomo Dal FabbroIRCCS Rizzoli Orthopaedic Institute - 2nd Orthopaedic and Trauma Department, Bologna, Italy. giacomo.dalfabbro@studio.unibo.it.
Giovanni BalboniIRCCS Rizzoli Orthopaedic Institute - 2nd Orthopaedic and Trauma Department, Bologna, Italy. giovanni.balboni@ior.it.
Stefano Di PaoloIRCCS Rizzoli Orthopaedic Institute - 2nd Orthopaedic and Trauma Department, Bologna, Italy.
Giorgio VarchettaIRCCS Rizzoli Orthopaedic Institute - 2nd Orthopaedic and Trauma Department, Bologna, Italy.
Alberto GrassiIRCCS Rizzoli Orthopaedic Institute - 2nd Orthopaedic and Trauma Department, Bologna, Italy.
Giulio Maria Marcheggiani MuccioliIRCCS Rizzoli Orthopaedic Institute - 2nd Orthopaedic and Trauma Department, Bologna, Italy.
Stefano ZaffagniniIRCCS Rizzoli Orthopaedic Institute - 2nd Orthopaedic and Trauma Department, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess long term survivorship, patient reported (PROMs) and radiological outcomes, and rate of adverse events and hardware removal after lateral closing wedge high tibial osteotomy (CWHTO) for the treatment of medial knee osteoarthritis (OA) and varus malalignment.

methodsRetrospective analysis of patients who underwent isolated CWHTO for medial OA in varus knee between 2009 and 2019 at the same institution was performed. Surgical failure was defined as conversion to total knee arthroplasty (TKA) or need for osteotomy revision procedure for varus recurrence, while clinical failure was defined by a Lysholm score under 65 points. Lysholm score, Visual Analogue Scale for pain (VAS), and patients' satisfaction with the treatment were evaluated. Radiographic parameters assessed included OA degree with the Kellgren Lawrence scale (KL), hip-knee-ankle angle (HKA), medial proximal tibial angle (MPTA), lateral distal femoral angle (LDFA), joint line convergence angle (JLCA), and posterior tibial slope (PTS). Adverse events and rate of hardware removal procedures were recorded through follow up visits and clinical records. Survival analysis was conducted through Kaplan-Meier method with surgical and clinical failure as endpoints.

results70 knees (mean age at surgery 43.3 years) were included in the survivorship analysis at a mean follow up of 11.6 ± 3.4 years. A failure rate of 12.85% (9/70) was recorded during the follow up period, with a survivorship of 92% and 75% at ten and 15 years of follow up, respectively. Mean Lysholm score and VAS at follow up were above the PASS threshold reported in literature. The 75.7% of patients were satisfied with the treatment. Radiological follow up indicated a residual mechanical varus of 2.1°, a decrease of 0.7° of intra articular deformity (JLCA), no change in PTS nor in KL index. The adverse events rate recorded was 5.7% (4/70). In nine knees (14.7%) among the patients survived from surgical failure a subsequent hardware removal procedure was performed.

conclusionCWHTO represents a safe procedure, which resulted in high survivorship (92% and 75% at ten and 15 years follow up, respectively), with satisfactory PROMs and radiological outcomes at long term follow up in patients affected by medial OA and varus malalignment. LEVEL OF EVIDENCE: 5, Case Series.

Indexed as

Osteoarthritis, KneeOsteotomyTibiaAdultAgedFemaleFollow-Up StudiesHumansKnee JointMaleMiddle AgedPatient Reported Outcome MeasuresPatient SatisfactionReoperationRetrospective StudiesTreatment OutcomeClosing wedgeComplicationsHigh tibial osteotomyOsteoarthritisSurvivorshipVarus knee

Identifiers

PMID40266312
PMCPMC12179228

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.