Evidence map›Paper›PMID 40266225›Full record

ArticleVaccines2025

Impact of the Implementation of a Bovine Viral Diarrhea Virus Targeted Vaccine in Dairy Farms: Longitudinal Analysis.

Demian Bellido, Diego Wenz, Martin Schang, Facundo Tibaldo Rubiolo, Pablo Mangioni, Emanuel Gumina, Andrés Wigdorovitz, Viviana Parreño

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Demian BellidoVetanco SA, Villa Martelli, Buenos Aires, CP 1603, Argentina.ORCID 0000-0003-1185-4709
Diego WenzVetanco SA, Villa Martelli, Buenos Aires, CP 1603, Argentina.
Martin SchangVetanco SA, Villa Martelli, Buenos Aires, CP 1603, Argentina.
Facundo Tibaldo RubioloVetanco SA, Villa Martelli, Buenos Aires, CP 1603, Argentina.
Pablo MangioniVetanco SA, Villa Martelli, Buenos Aires, CP 1603, Argentina.
Emanuel GuminaVetanco SA, Villa Martelli, Buenos Aires, CP 1603, Argentina.
Andrés WigdorovitzBioinnovo SA, Villa Martelli, Buenos Aires, CP1603, Argentina.
Viviana ParreñoIncuinta, IVIT INTA, Hurlingham, Buenos Aires, CP1686, Argentina.ORCID 0000-0003-0385-5592

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study evaluated the effect of a novel subunit-targeted vaccine against BVDV in six dairy farms in Argentina.

methodsReproductive, health, and production parameters-including conception and abortion rates, open days, calves born per insemination, as well as newborn and overall mortality, and milk production-were monitored over a ten-year period (2014-2023). Data were analyzed annually to assess trends and compare the periods before and after vaccine introduction.

resultsAll parameters showed significant improvement after vaccine incorporation, with an 11% increase in conception rate, a 5% reduction in abortion rate, a 12% increase in calves per insemination rate, and a decrease of 11 open days (8.4%). Additionally, newborn mortality and overall mortality decreased by 33% and 16%, respectively, while milk production increased by 9%. These data were also compared with eight non-vaccinated dairy farms, and significant differences were observed in health and reproductive parameters.

conclusionsThese findings indicate that vaccination with an effective non-replicating subunit vaccine can successfully minimize the impact of BVDV in dairy farms.

Indexed as

bovine viral diarrhea virusdairy farmtargeted vaccine

Identifiers

PMID40266225
PMCPMC11946228

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.