Evidence map›Paper›PMID 40266205›Full record

ArticleVaccines2025

Stabilizing Prefusion SARS-CoV-2 Spike by Destabilizing the Postfusion Conformation.

Debajyoti Chakraborty, Randhir Singh, Raju S Rajmani, Sahil Kumar, Rajesh P Ringe, Raghavan Varadarajan

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Debajyoti ChakrabortyMolecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India.
Randhir SinghMynvax Private Limited, 3rd Floor, Brigade MLR Centre, No.50, Vani Vilas Road, Basavanagudi, Bengaluru 560004, India.ORCID 0000-0001-7388-225X
Raju S RajmaniMolecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India.
Sahil KumarVirology Unit, Institute of Microbial Technology, Council of Scientific and Industrial Research (CSIR), Chandigarh 160036, India.
Rajesh P RingeVirology Unit, Institute of Microbial Technology, Council of Scientific and Industrial Research (CSIR), Chandigarh 160036, India.ORCID 0000-0002-6068-4163
Raghavan VaradarajanMolecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India.ORCID 0000-0002-0823-7577

Funding

Bill & Melinda Gates Foundation INV-042471
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

charged amino acidsCOVID-19HR1 and HR2immunogenicitySARS-CoV-2 Spikestabilization

Identifiers

PMID40266205
PMCPMC11946859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.