Evidence map›Paper›PMID 40266123›Full record

ArticleVaccines2025

Type I Interferon Modulates the Function of Ly6C High-Expressing Naïve CD8

Hsin-Fang Tu, Julia Tao, Ming-Hung Hu, Darrell Fan, Ya-Chea Tsai, Tzyy-Choou Wu, Chien-Fu Hung

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hsin-Fang TuDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0009-0008-9048-493X
Julia TaoDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Ming-Hung HuDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-9923-0281
Darrell FanDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0002-5286-5183
Ya-Chea TsaiDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Tzyy-Choou WuDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Chien-Fu HungDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Funding

Treatment of HIV- and HIV+ Patients with HPV16+ CIN2/3 Using pNGLV4a-hCRTE6E7L2 DNA vaccine administered intramuscularly via electroporationP50CA098252 · NCI · JOHNS HOPKINS UNIVERSITY · PI TZYY-CHOOU WU · 2003 to 2026
$53.5M
Development of Novel Spontaneous HPV Cervicovaginal Carcinoma Models for Cancer ImmunotherapyR01CA237067 · NCI · JOHNS HOPKINS UNIVERSITY · PI WU, TZYY-CHOOU · 2019 to 2023
$2.9M
Novel strategy combined with targeted radiation therapy unleashes potentantitumor immunity in HPV + head and neck cancerR21CA256020 · NCI · JOHNS HOPKINS UNIVERSITY · PI HUNG, CHIEN-FU · 2021 to 2022
$417k
NCI NIH HHS 1R21CA234516-01A1NCI NIH HHS P50 CA098252NCI NIH HHS P50CA098252NCI NIH HHS R01CA237067NCI NIH HHS R21CA256020NCI NIH HHS R21DE029910-01
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer immunotherapyimmune modulationLy6Chi CD8 T cellstype I interferon

Identifiers

PMID40266123
PMCPMC11945601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.