Evidence map›Paper›PMID 40266059›Full record

ArticleVaccines2025

Knowledge About HPV and the HPV Vaccine: Observational Study on a Convenience Sample of Adolescents from Select Schools in Three Regions in Italy.

Laura Brunelli, Francesca Valent, Manola Comar, Barbara Suligoi, Maria Cristina Salfa, Daniele Gianfrilli, Franz Sesti, Giuseppina Capra, Alessandra Casuccio, Erik De Luca and 9 more

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Human Papillomavirus: An Old New History.Pathogens (Basel, Switzerland) · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Laura BrunelliDipartimento di Medicina, Università degli Studi di Udine, 33100 Udine, Italy.ORCID 0000-0002-5475-0021
Francesca ValentSOC Igiene e Sanità Pubblica, Dipartimento di Prevenzione, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.ORCID 0000-0002-4071-0897
Manola ComarDiagnostica Avanzata Microbiologica Traslazionale, IRCSS Burlo Garofolo, 34137 Trieste, Italy.
Barbara SuligoiCentro Operativo AIDS, Dipartimento Malattie Infettive, Istituto Superiore di Sanità, 00161 Rome, Italy.
Maria Cristina SalfaCentro Operativo AIDS, Dipartimento Malattie Infettive, Istituto Superiore di Sanità, 00161 Rome, Italy.
Daniele GianfrilliDipartimento di Medicina Sperimentale, Università Sapienza di Roma, 00185 Rome, Italy.
Franz SestiDipartimento di Medicina Sperimentale, Università Sapienza di Roma, 00185 Rome, Italy.ORCID 0000-0003-3850-627X
Giuseppina CapraSezione di Microbiologia, Dipartimento PROMISE, Università di Palermo, 90127 Palermo, Italy.ORCID 0000-0002-1407-7282
Alessandra CasuccioSezione di Igiene, Dipartimento PROMISE, Università di Palermo, 90127 Palermo, Italy.ORCID 0000-0002-5676-9535
Erik De LucaSOC Accreditamento, Qualità e Rischio Clinico, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.
Emily BertolaSOC Igiene e Sanità Pubblica, Dipartimento di Prevenzione, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.
Silvia GazzettaDipartimento di Medicina, Università degli Studi di Udine, 33100 Udine, Italy.
Lorenza DriulSOC Ostetricia e Ginecologia, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.
Andrea IsidoriDipartimento di Medicina Sperimentale, Università Sapienza di Roma, 00185 Rome, Italy.
Patrizia FerroSezione di Igiene, Dipartimento PROMISE, Università di Palermo, 90127 Palermo, Italy.ORCID 0009-0004-4435-6997
Nicolò PiazzaSezione di Igiene, Dipartimento PROMISE, Università di Palermo, 90127 Palermo, Italy.ORCID 0009-0009-1422-456X
Palmira ImmordinoSezione di Igiene, Dipartimento PROMISE, Università di Palermo, 90127 Palermo, Italy.ORCID 0000-0002-1051-6874
Teresa FascianaSezione di Microbiologia, Dipartimento PROMISE, Università di Palermo, 90127 Palermo, Italy.
Vincenzo RestivoDipartimento di Medicina, Università Kore di Enna, 94100 Enna, Italy.

Funding

the Italian Ministry of Health-CCM
6 · The paper itself

Abstract

BACKGROUND/

objectivesHPV is the most common sexually transmitted infectious agent worldwide and adolescents are at high risk of contracting HPV. The aim of our study was to find out how much adolescents know about the virus and its effects, and to obtain information on attitudes and behaviors regarding HPV vaccination to close these gaps.

methodsAs part of the ESPRIT project, 598 lower secondary (11-14 years) and upper secondary (14-19 years) school students from three Italian regions were surveyed between December 2023 and March 2024 using a seven-question online questionnaire on awareness, knowledge, and attitudes about HPV and the HPV vaccine. Count and zero-inflation models were used to determine correlations between sexes, urban/suburban, province of residence, and school type with knowledge.

resultsLower secondary students believed that HPV causes HIV/AIDS (8.9%) or hepatitis C (3.0%) and rarely mentioned anal (21%) and oral sex (9.6%) as ways of transmission. Among upper secondary students, misconceptions were similar, with worrying rates of students stating that HPV only causes cancer in females (18%) or males (2.4%), and low rates of identifying transmission risk through anal (41%) and oral (34%) sex and genital contact (38%). The HPV vaccination rate was quite low (47% in lower secondary students, 61% in upper secondary students). In the regressions, sex, urban/suburban area, and province were the variables associated with higher levels of knowledge for lower secondary students; for upper secondary students, level of knowledge was associated with sex, urban/suburban area, school type, and province of residence.

conclusionsAwareness and knowledge of HPV and the HPV vaccine are low among Italian students in this study and reported vaccination coverage is below the national target. Coordinated efforts at the national level are needed to address this public health issue.

Indexed as

adolescentsHPVpreventionpublic healthschool

Identifiers

PMID40266059
PMCPMC11946237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.