Evidence map›Paper›PMID 40265946›Full record

ArticleClinical nuclear medicine2025

Use of 68 Ga-labeled Macroaggregated Albumin Particles for Selective Internal Radiation Therapy (SIRT) Dosimetry and Treatment Planning.

Christian Goetz, Michael Christian Doppler, Mohamed Aymen Omrane, Wibke Uller, Philipp Tobias Meyer

Abstract readCase Reports
In one paragraph

Article in Clinical nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christian GoetzDepartments of Nuclear Medicine.
Michael Christian DopplerDiagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Mohamed Aymen OmraneDepartments of Nuclear Medicine.
Wibke UllerDiagnostic and Interventional Radiology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Philipp Tobias MeyerDepartments of Nuclear Medicine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In October 2024, Europe again experienced a period of shortage of technetium-labeled tracers. In order not to delay time-critical treatments of liver tumors, we turned to 68 Ga-labeled macroaggregated albumin particles ([ 68 Ga]Ga-MAA) as already used for lung perfusion PET imaging for selective internal radiation therapy (SIRT) dosimetry and treatment planning. Labeling was performed under GMP conditions and could be applied for SIRT planning in one patient. Post-therapy dosimetry based on [ 90 Y]microsphere PET/CT demonstrated excellent agreement. Dosimetry and treatment planning with [ 68 Ga]Ga-MAA should be considered as a viable alternative to [ 99m Tc]Tc-MAA SPECT/CT and could be considered for routine use.

Indexed as

AlbuminsGallium RadioisotopesRadiotherapy Planning, Computer-AssistedHumansIsotope LabelingLiver NeoplasmsPositron Emission Tomography Computed TomographyRadiometryAlbuminsGallium-68Gallium RadioisotopesSIRT dosimetryTARE dosimetrytechnetium shortage

Identifiers

PMID40265946
PMCPMC12208377

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.